Cephalexin and Wakix drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cephalexin (cephalexin) and Wakix (pitolisant hydrochloride). Common drug interactions include fatigue among females and anxiety among males.

The phase IV clinical study analyzes what interactions people have when they take Cephalexin and Wakix. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Cephalexin?

Cephalexin has active ingredients of cephalexin. It is often used in infection. eHealthMe is studying from 30,580 Cephalexin users. Check the latest studies of Cephalexin.

What is Wakix?

Wakix has active ingredients of pitolisant hydrochloride. eHealthMe is studying from 1,982 Wakix users. Check the latest studies of Wakix.

On Jul, 13, 2026

17 people who take Cephalexin and Wakix together, and have interactions are studied.

What are the common drug interactions of Cephalexin and Wakix, by gender? *:

female:

Fatigue (feeling of tiredness)
Surgery
Depression
Serotonin syndrome (occurs when two drugs that affect the body's level of serotonin are taken together at the same time)
Nephrolithiasis (calculi in the kidneys)
Skin ulcer
Malaise (a feeling of general discomfort or uneasiness)
Sinus headache (headache caused by sinus infections)

male:

Anxiety
Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
Eye pain
Fatigue (feeling of tiredness)
Feeling drunk
Headache (pain in head)
Homicidal ideation (thoughts about human killing another human)
Irritability
Lethargy (tiredness)
Nasopharyngitis (inflammation of the nasopharynx)

What are the common drug interactions of Cephalexin and Wakix, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Autism spectrum disorder (developmental disabilities that can cause significant social, communication and behavioural challenges)
Bipolar disorder (mood disorder)
Catatonia (unresponsive to external stimuli)
Depression
Drug dependence
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Encephalitis autoimmune (autoimmune origin disturbances of consciousness and pyramidal signs, inflammation of the brain)
Eye pain

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Fatigue (feeling of tiredness)
Surgery
Sinus headache (headache caused by sinus infections)

60+:

Abnormal dreams
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Arthropathy
Full blood count decreased
Pain
Pruritus (severe itching of the skin)
Sinus headache (headache caused by sinus infections)
Skin exfoliation (removal of the oldest dead skin cells)
Anaemia (lack of blood)
Blood chloride decreased

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 17 people, 100.00%
Drowsiness: 4 people, 23.53%
Cataplexy (loss of muscle tone accompanied by full conscious awareness): 4 people, 23.53%

* Approximation only. Some reports may have incomplete information.

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