Prevalite and Metformin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Prevalite (cholestyramine) and Metformin (metformin hydrochloride). Common drug interactions include renal failure among females and weight decreased among males.

The phase IV clinical study analyzes what interactions people have when they take Prevalite and Metformin. It is created by eHealthMe based on reports of 51 people who take the same drugs from the FDA, and is updated regularly.

What is Prevalite?

Prevalite has active ingredients of cholestyramine. eHealthMe is studying from 749 Prevalite users. Check the latest studies of Prevalite.

What is Metformin?

Metformin has active ingredients of metformin hydrochloride. It is often used in diabetes. eHealthMe is studying from 465,354 Metformin users. Check the latest studies of Metformin.



On Jul, 13, 2026

51 people who take Prevalite and Metformin together, and have interactions are studied.

Prevalite and Metformin drug interactions.

What are the common drug interactions of Prevalite and Metformin, by gender? *:

female:

  1. Renal failure (kidney dysfunction)
  2. Chronic kidney disease
  3. Nephropathy (damage to or disease of a kidney)
  4. Fatigue (feeling of tiredness)
  5. Gout (uric acid crystals building up in the body)
  6. Peripheral swelling
  7. Weight decreased
  8. Acute pulmonary oedema (sudden deposit of fluid in the lung))
  9. Arthralgia (joint pain)
  10. Asthenia (weakness)

male:

  1. Weight decreased
  2. Back pain
  3. Ankle fracture
  4. Asthenia (weakness)
  5. Balance disorder
  6. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  7. Dyspnoea (difficult or laboured respiration)
  8. Gingival bleeding (bleeding gums)
  9. Haematuria (presence of blood in urine)
  10. Hepatic mass

What are the common drug interactions of Prevalite and Metformin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

  1. Blood calcium increased
  2. Blood sodium decreased
  3. Dehydration (dryness resulting from the removal of water)
  4. Exostosis (formation of new bone on the surface of a bone)
  5. Intervertebral disc degeneration (spinal disc degeneration)
  6. Pruritus (severe itching of the skin)

50-59:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Ankle fracture
  3. Anxiety
  4. Balance disorder
  5. Emotional distress
  6. Multiple fractures
  7. Muscular weakness (muscle weakness)
  8. Osteomalacia (softening of the bones due to a lack of vitamin d)
  9. Osteopenia (a condition where bone mineral density is lower than normal)
  10. Pain

60+:

  1. Weight decreased
  2. Renal failure (kidney dysfunction)
  3. Night sweats (sweating in night)
  4. Red blood cell count decreased
  5. Bone lesion (bone with abnormalities. bone lesions can result from growth formations, infections, or injuries)
  6. Diarrhoea
  7. Dyspnoea (difficult or laboured respiration)
  8. Fatigue (feeling of tiredness)
  9. Gingival bleeding (bleeding gums)
  10. Gout (uric acid crystals building up in the body)

What are the existing conditions these people have? *

  1. High Blood Pressure: 8 people, 15.69%
  2. Multiple Myeloma (cancer of the plasma cells): 8 people, 15.69%
  3. High Blood Cholesterol: 7 people, 13.73%
  4. Diarrhea: 6 people, 11.76%
  5. Pain: 5 people, 9.80%
  6. Chronic Lymphocytic Leukaemia (cancer in which the bone marrow makes too many lymphocytes (a type of white blood cell)): 5 people, 9.80%
  7. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 7.84%
  8. Lymphocytic Leukaemia (a type of cancer in which the bone marrow makes too many lymphocytes): 4 people, 7.84%
  9. Neuralgia (pain in one or more nerves): 4 people, 7.84%
  10. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 7.84%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Prevalite and Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Prevalite:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Metformin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Prevalite and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Metformin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cholestyramine and metformin hydrochloride (the active ingredients of Prevalite and Metformin, respectively), and Prevalite and Metformin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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