Cerezyme and Clonidine drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cerezyme (imiglucerase) and Clonidine (clonidine). Common drug interactions include dyspnoea among females and mobility decreased among males.
The phase IV clinical study analyzes what interactions people have when they take Cerezyme and Clonidine. It is created by eHealthMe based on reports of 18 people who take the same drugs from the FDA, and is updated regularly.
What is Cerezyme?
Cerezyme has active ingredients of imiglucerase. eHealthMe is studying from 6,451 Cerezyme users. Check the latest studies of Cerezyme.
What is Clonidine?
Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.
18 people who take Cerezyme and Clonidine together, and have interactions are studied.

What are the common drug interactions of Cerezyme and Clonidine, by gender? *:
female:
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Bone disorder
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Dehydration (dryness resulting from the removal of water)
- Depression
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Generalised oedema (swelling all over the body)
- Heart rate increased
male:
- Mobility decreased (ability to move is reduced)
- Peripheral swelling
- General physical health deterioration (weak health status)
- Gout (uric acid crystals building up in the body)
- Hepatosplenomegaly (enlargement of both the liver and the spleen)
- Injury
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Pain
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
What are the common drug interactions of Cerezyme and Clonidine, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
- Mobility decreased (ability to move is reduced)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Upper respiratory tract infection
- Weight increased
- Death
10-19:
- Dyspnoea (difficult or laboured respiration)
- Encephalopathy (functioning of the brain is affected by some agent or condition)
- Pneumonia
- Respiratory distress (difficulty in breathing)
- Seizure (abnormal excessive or synchronous neuronal activity in the brain)
- Septic shock (shock due to blood infection)
- Stridor
- Vocal cord disorder
- Weight decreased
20-29:
n/a
30-39:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Dehydration (dryness resulting from the removal of water)
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Generalised oedema (swelling all over the body)
- Lupus nephritis (a chronic inflammatory autoimmune disorder that may affect kidney tissue)
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Migraine (headache)
- Renal failure (kidney dysfunction)
- Reversible posterior leukoencephalopathy syndrome (a brain disease with generalized seizures and headache)
- Systemic lupus erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue)
40-49:
n/a
50-59:
- Arthralgia (joint pain)
- Arthritis infective (purulent invasion of a joint by an infectious agent which produces arthritis)
- Central line infection (infection by central line in icu)
- Gout (uric acid crystals building up in the body)
- Hepatosplenomegaly (enlargement of both the liver and the spleen)
- Medical device complication
- Staphylococcal infection (an infection with staphylococcus bacteria)
60+:
- Bone disorder
- Depression
- Peripheral swelling
- Abdominal discomfort
- Fall
- Hip fracture
- Dyspnoea (difficult or laboured respiration)
- Fatigue (feeling of tiredness)
- Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
- Heart rate increased
What are the existing conditions these people have? *
- Pain: 2 people, 11.11%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 5.56%
- Asthma: 1 person, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Cerezyme and Clonidine?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cerezyme and Clonidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cerezyme:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clonidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cerezyme and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clonidine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
- Teimoory M, Arefi M, Behnoush B, Bastani B, "Promethazine and Treatment Refractory Agitation in Clonidine Toxicity", International Journal of Medical Toxicology and Forensic Medicine, 2013 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on imiglucerase and clonidine (the active ingredients of Cerezyme and Clonidine, respectively), and Cerezyme and Clonidine (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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