Cetirizine hydrochloride and Chlorpheniramine maleate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cetirizine hydrochloride (cetirizine hydrochloride) and Chlorpheniramine maleate (chlorpheniramine maleate). Common drug interactions include maternal exposure during pregnancy among females and cerebral infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Cetirizine hydrochloride and Chlorpheniramine maleate. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Cetirizine hydrochloride?

Cetirizine hydrochloride has active ingredients of cetirizine hydrochloride. It is often used in allergies. eHealthMe is studying from 34,908 Cetirizine hydrochloride users. Check the latest studies of Cetirizine hydrochloride.

What is Chlorpheniramine maleate?

Chlorpheniramine maleate has active ingredients of chlorpheniramine maleate. It is often used in allergies. eHealthMe is studying from 7,632 Chlorpheniramine maleate users. Check the latest studies of Chlorpheniramine maleate.

On Jul, 10, 2026

55 people who take Cetirizine hydrochloride and Chlorpheniramine maleate together, and have interactions are studied.

Cetirizine hydrochloride and Chlorpheniramine maleate drug interactions.

What are the common drug interactions of Cetirizine Hydrochloride and Chlorpheniramine Maleate, by gender? *:

female:

Maternal exposure during pregnancy (use of substance during pregnancy)
Nasal turbinate hypertrophy (nasal turbinates become enlarged)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Oxygen saturation decreased
Respiratory disorder (respiratory disease)
Rhinitis (a medical term for irritation and inflammation of the mucous membrane inside the nose)
Rhonchi (abnormal breath sounds)
Sinus tachycardia (a heart rhythm with elevated rate of impulses originating from the sinoatrial node)
Sinusitis (inflammation of sinus)
Weight increased

male:

Cerebral infarction (less blood supply to brain resulting tissue damage)
Dyslipidaemia (abnormal amount of lipids)
Pruritus (severe itching of the skin)
Urinary tract infection
Cutaneous vasculitis (an inflammatory process affecting the vessel wall that leads to its damage)
Diarrhoea
Dyskinesia (abnormality or impairment of voluntary movement)
Eczema (patches of skin become rough and inflamed, with itching and bleeding blisters)
Hip arthroplasty
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Cetirizine Hydrochloride and Chlorpheniramine Maleate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Humerus fracture (injury to the upper arm bone)

10-19:

Hip arthroplasty

20-29:

n/a

30-39:

Cutaneous vasculitis (an inflammatory process affecting the vessel wall that leads to its damage)
Anaemia (lack of blood)
Asthenia (weakness)
Blood pressure diastolic decreased
Body temperature decreased
Dry mouth
Electrocardiogram st segment elevation
Fatigue (feeling of tiredness)
Gastric ulcer haemorrhage (bleeding ulcer of stomach)
Heart rate irregular

40-49:

n/a

50-59:

Dyspnoea (difficult or laboured respiration)
Granuloma (a small area of inflammation due to tissue injury)
Herpes zoster
Hypersensitivity
Infection
Lower respiratory tract infection
Maternal exposure during pregnancy (use of substance during pregnancy)
Nasal turbinate hypertrophy (nasal turbinates become enlarged)
Obstructive airways disorder (a progressive disease that makes it hard to breathe)
Oxygen saturation decreased

60+:

Diarrhoea
Pruritus (severe itching of the skin)
Appendicitis (inflammation of the appendix)
Axillary pain
Catheter site haemorrhage (bleeding at catheter site)
Chest discomfort
Constipation
Dementia (madness)
Ejection fraction decreased (systolic heart failure)
Lacrimation increased

What are the existing conditions these people have? *

Itching: 13 people, 23.64%
Breast Cancer Metastatic: 10 people, 18.18%
Diarrhea: 9 people, 16.36%
Hypersensitivity: 7 people, 12.73%
Insomnia (sleeplessness): 7 people, 12.73%
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood): 6 people, 10.91%
Asthma: 6 people, 10.91%
Urinary Incontinence (inability to control the flow of urine and involuntary urination): 6 people, 10.91%
Hypokalemia (low potassium): 6 people, 10.91%
Infection: 6 people, 10.91%

* Approximation only. Some reports may have incomplete information.

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