Lamisil and Bextra drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Lamisil (terbinafine hydrochloride) and Bextra (valdecoxib). Common drug interactions include urinary sediment present among females and abdominal distension among males.

The phase IV clinical study analyzes what interactions people have when they take Lamisil and Bextra. It is created by eHealthMe based on reports of 17 people who take the same drugs from the FDA, and is updated regularly.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.

What is Bextra?

Bextra has active ingredients of valdecoxib. It is often used in pain. eHealthMe is studying from 20,994 Bextra users. Check the latest studies of Bextra.

On Jul, 10, 2026

17 people who take Lamisil and Bextra together, and have interactions are studied.

What are the common drug interactions of Lamisil and Bextra, by gender? *:

female:

Urinary sediment present
Urine leukocyte esterase positive
Vaginal haemorrhage (vaginal bleeding)
Amenorrhoea (absence of a menstrual period in a woman of reproductive age)
Anaphylactic reaction (serious allergic reaction)
Blood cholesterol increased
Blood urine present
Breast cancer in situ
Breast pain
Cerebellar syndrome (impaired blood circulation to cerebellum due to lesion in artery)

male:

Abdominal distension
Acute myocardial infarction (acute heart attack)
Anxiety
Ascites (accumulation of fluid in the abdominal cavity)
Asthenia (weakness)
Chest pain
Contusion (a type of hematoma of tissue in which capillaries)
Fall
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Hyperchlorhydria (gastric acid levels are higher in stomach)

What are the common drug interactions of Lamisil and Bextra, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

Abdominal distension
Hepatitis c
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Abdominal pain
Ascites (accumulation of fluid in the abdominal cavity)
Contusion (a type of hematoma of tissue in which capillaries)
Drug ineffective
Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
Rash
Spider naevus (small dilated blood vessels near the surface of the skin)

50-59:

Chest pain
Drug toxicity
Epicondylitis (tennis elbow)
Exostosis (formation of new bone on the surface of a bone)
Fall
Flat affect (absence of emotional response to a situation)
Foot deformity (functional disability of foot)
Gastric mucosa erythema (reddened mucosa of stomach)
Headache (pain in head)
Hyperchlorhydria (gastric acid levels are higher in stomach)

60+:

Tremor (trembling or shaking movements in one or more parts of your body)
Alcoholism (problems with alcohol)
Cataract (clouding of the lens inside the eye)
Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
Chronic kidney disease
Dermatitis (inflammation of the skin resulting from direct irritation by an external agent or an allergic reaction to it)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Dysphagia (a condition in which swallowing is difficult or painful)
Eyelid ptosis (falling of the upper or lower eyelid)
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Nail Tinea (fungal infection of nail): 3 people, 17.65%
Depression: 3 people, 17.65%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 3 people, 17.65%
Tremor (trembling or shaking movements in one or more parts of your body): 2 people, 11.76%
Rashes (redness): 2 people, 11.76%
Gastrointestinal Disorder (functional problems of gastrointestinal tract): 2 people, 11.76%
Stress And Anxiety: 1 person, 5.88%
Musculoskeletal Discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves): 1 person, 5.88%
Ill-Defined Disorder: 1 person, 5.88%
Gastrointestinal Haemorrhage (bleeding gastrointestinal tract): 1 person, 5.88%

* Approximation only. Some reports may have incomplete information.

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