Ozempic and Maculopathy - a phase IV clinical study of FDA data

Summary:

Maculopathy is reported as a side effect among people who take Ozempic (semaglutide), especially for people who are female, 20-29 old, have been taking the drug for < 1 month also take Novorapid, and have High blood pressure.

The phase IV clinical study analyzes which people have Maculopathy when taking Ozempic. It is created by eHealthMe based on reports of 28,954 people who have side effects when taking Ozempic from the FDA, and is updated regularly.

What is Ozempic?

Ozempic has active ingredients of semaglutide. It is often used in weight loss. eHealthMe is studying from 29,761 Ozempic users. Check the latest studies of Ozempic.

What is Maculopathy?

Maculopathy (a condition or disease of the macula, the small spot in the retina where vision is keenest) is found to be associated with 380 drugs and 726 conditions by eHealthMe. Check the latest studies of Maculopathy.



On Jul, 10, 2026

28,954 people reported to have side effects when taking Ozempic.
Among them, 16 people (0.06%) have Maculopathy.

Could Ozempic cause Maculopathy?

Among these 16 people:

How long have people been on Ozempic when they have Maculopathy? *

  • < 1 month: 90.91 %
  • 1 - 6 months: 0.0 %
  • 6 - 12 months: 0.0 %
  • 1 - 2 years: 9.09 %
  • 2 - 5 years: 0.0 %
  • 5 - 10 years: 0.0 %
  • 10+ years: 0.0 %

What is the gender of people who have Maculopathy when taking Ozempic? *

  • female: 87.5 %
  • male: 12.5 %

What is the age of people who have Maculopathy when taking Ozempic? *

  • 0-1: 0.0 %
  • 2-9: 0.0 %
  • 10-19: 0.0 %
  • 20-29: 64.29 %
  • 30-39: 0.0 %
  • 40-49: 0.0 %
  • 50-59: 7.14 %
  • 60+: 28.57 %

What are other drugs people take besides Ozempic? *

  1. Novorapid: 10 people, 62.50%
  2. Metformin: 3 people, 18.75%
  3. Temazepam: 3 people, 18.75%
  4. Elmiron: 3 people, 18.75%
  5. Synthroid: 2 people, 12.50%
  6. Potassium Citrate: 2 people, 12.50%
  7. Carvedilol: 2 people, 12.50%
  8. Glimepiride: 2 people, 12.50%
  9. Uloric: 2 people, 12.50%
  10. Nascobal: 2 people, 12.50%

What are other side effects people have besides Maculopathy? *

  1. Abdominal Pain Lower: 8 people, 50.00%
  2. Detachment Of Retinal Pigment Epithelium: 2 people, 12.50%
  3. Depression: 2 people, 12.50%
  4. Blindness Unilateral: 2 people, 12.50%
  5. Visual Acuity Reduced (reduced clearness of vision): 1 person, 6.25%
  6. Neuropathy Peripheral (surface nerve damage): 1 person, 6.25%
  7. Glycosylated Haemoglobin Decreased: 1 person, 6.25%
  8. Diabetic Retinopathy (damage to the retina caused by complications of diabetes): 1 person, 6.25%

What are the existing conditions these people have? *

  1. High Blood Pressure: 11 people, 68.75%
  2. Type 2 Diabetes: 10 people, 62.50%
  3. Birth Control: 9 people, 56.25%
  4. Ocular Hypertension (intraocular pressure higher than normal): 9 people, 56.25%
  5. Dyslipidaemia (abnormal amount of lipids): 9 people, 56.25%
  6. Diabetes: 4 people, 25.00%
  7. High Blood Cholesterol: 3 people, 18.75%
  8. Sleep Disorder: 3 people, 18.75%
  9. Cystitis Interstitial (unknown cause characterized by bladder pain): 3 people, 18.75%
  10. Hypertonic Bladder (bladder-storage function that causes a sudden urge to urinate): 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

Do you take Ozempic and have Maculopathy?

- Check whether Maculopathy is associated with a drug or a condition
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, long term effects of, and alternative drugs to Ozempic:

Maculopathy treatments and more:

How severe was Maculopathy and when was it recovered:

Expand to all the drugs that have ingredients of semaglutide:

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Ozempic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all the drugs that are associated with Maculopathy:

Browse all the conditions that are associated with Maculopathy:


How the study uses the data?

The study uses data from the FDA. It is based on semaglutide (the active ingredients of Ozempic) and Ozempic (the brand name). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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