Xanax and Aceon drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Xanax (alprazolam) and Aceon (perindopril erbumine). Common drug interactions include back pain among females and drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Xanax and Aceon. It is created by eHealthMe based on reports of 34 people who take the same drugs from the FDA, and is updated regularly.

What is Xanax?

Xanax has active ingredients of alprazolam. It is often used in stress and anxiety. eHealthMe is studying from 135,347 Xanax users. Check the latest studies of Xanax.

What is Aceon?

Aceon has active ingredients of perindopril erbumine. It is often used in high blood pressure. eHealthMe is studying from 1,785 Aceon users. Check the latest studies of Aceon.



On Jul, 10, 2026

34 people who take Xanax and Aceon together, and have interactions are studied.

Xanax and Aceon drug interactions.

What are the common drug interactions of Xanax and Aceon, by gender? *:

female:

  1. Back pain
  2. Blood pressure decreased
  3. Cardiac disorder
  4. Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
  5. Confusional state
  6. Conjunctival hyperaemia (congestion of conjunctival vessels)
  7. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  8. Crying
  9. Disturbance in attention
  10. Duodenitis (inflammation of the duodenum)

male:

  1. Drug ineffective
  2. Depression
  3. Cough
  4. Diarrhoea
  5. Diplopia (double vision)
  6. Dyspnoea (difficult or laboured respiration)
  7. Eye disorder
  8. Eyelid ptosis (falling of the upper or lower eyelid)
  9. Gait disturbance
  10. Gastrointestinal pain

What are the common drug interactions of Xanax and Aceon, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Chest pain
  2. Circadian rhythm sleep disorder (family of sleep disorders affecting, among other things, the timing of sleep)
  3. Confusional state
  4. Crying
  5. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  6. Diarrhoea
  7. Duodenitis (inflammation of the duodenum)
  8. Dysfunctional uterine bleeding
  9. Dysmenorrhoea (painful menstruation)
  10. Dyspepsia (indigestion)

30-39:

n/a

40-49:

  1. Aggression
  2. Angina unstable (chest pain due to ischemia of the heart muscle- unstable)
  3. Bipolar disorder (mood disorder)
  4. Bladder cancer
  5. Cardiac failure congestive
  6. Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
  7. Depression
  8. Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
  9. Hypertensive heart disease
  10. Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)

50-59:

  1. Angioedema (rapid swelling of the dermis)
  2. Cough
  3. Pulmonary oedema (fluid accumulation in the lungs)
  4. Cardiac failure
  5. Dyspnoea (difficult or laboured respiration)
  6. Erythema (redness of the skin)
  7. Hypersensitivity
  8. Left ventricular failure (left ventricle fails to contract forcefully)
  9. Listless (lack of interest, energy, or spirit)
  10. Nausea (feeling of having an urge to vomit)

60+:

  1. Weight decreased
  2. Arthralgia (joint pain)
  3. Asthenia (weakness)
  4. Bacterial infection
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Cough
  7. Diarrhoea
  8. Drug ineffective
  9. Dysphonia (speech disorder attributable to a disorder of phonation)
  10. Ear congestion

What are the existing conditions these people have? *

  1. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 4 people, 11.76%
  2. Quit Smoking: 4 people, 11.76%
  3. Depression: 4 people, 11.76%
  4. Pain: 3 people, 8.82%
  5. High Blood Cholesterol: 3 people, 8.82%
  6. Emphysema (chronic respiratory disease - over inflation of the air sacs (alveoli) in the lungs): 3 people, 8.82%
  7. Bipolar Disorder (mood disorder): 3 people, 8.82%
  8. Synovitis (inflammation of the synovial membrane): 2 people, 5.88%
  9. Myasthenia Gravis (a chronic condition that causes muscles to tire and weaken easily): 2 people, 5.88%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 5.88%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Xanax and Aceon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Xanax:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aceon:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Xanax and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aceon and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on alprazolam and perindopril erbumine (the active ingredients of Xanax and Aceon, respectively), and Xanax and Aceon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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