Cevimeline and Ultram drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cevimeline (cevimeline hydrochloride) and Ultram (tramadol hydrochloride). Common drug interactions include dizziness among females.

The phase IV clinical study analyzes what interactions people have when they take Cevimeline and Ultram. It is created by eHealthMe based on reports of 20 people who take the same drugs from the FDA, and is updated regularly.

What is Cevimeline?

Cevimeline has active ingredients of cevimeline hydrochloride. It is often used in sjogren syndrome. eHealthMe is studying from 1,480 Cevimeline users. Check the latest studies of Cevimeline.

What is Ultram?

Ultram has active ingredients of tramadol hydrochloride. It is often used in pain. eHealthMe is studying from 28,425 Ultram users. Check the latest studies of Ultram.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 01, 2026

20 people who take Cevimeline and Ultram together, and have interactions are studied.

Cevimeline and Ultram drug interactions.

What are the common drug interactions of Cevimeline and Ultram, by gender? *:

female:

Dizziness
Nausea (feeling of having an urge to vomit)
Confusional state
Depression suicidal (suicide depressive disorder)
Incontinence (lack of moderation or self-control)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Attention deficit/hyperactivity disorder
Contusion (a type of hematoma of tissue in which capillaries)
Disability
Fall

male:

n/a

What are the common drug interactions of Cevimeline and Ultram, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

Abdominal pain upper
Nausea (feeling of having an urge to vomit)
Vomiting

60+:

Agitation (state of anxiety or nervous excitement)
Communication disorder (speech and language disorder)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Abdominal discomfort
Activities of daily living impaired
Arthralgia (joint pain)
Asthenia (weakness)
Dyspepsia (indigestion)
Fall
Fatigue (feeling of tiredness)

What are the existing conditions these people have? *

Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 14 people, 70.00%
Fibromyalgia (a long-term condition which causes pain all over the body): 3 people, 15.00%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 10.00%
Inflammation: 2 people, 10.00%
Depression: 2 people, 10.00%
Dry Mouth: 2 people, 10.00%
Bone Pain: 2 people, 10.00%
Multiple Allergies (allergy to multiple agents): 1 person, 5.00%
Migraine (headache): 1 person, 5.00%
Itching: 1 person, 5.00%

* Approximation only. Some reports may have incomplete information.

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