Chantix and Rabeprazole drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chantix (varenicline tartrate) and Rabeprazole (rabeprazole sodium). Common drug interactions include blood glucose increased among females and anorexia among males.

The phase IV clinical study analyzes what interactions people have when they take Chantix and Rabeprazole. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Chantix?

Chantix has active ingredients of varenicline tartrate. It is often used in quit smoking. eHealthMe is studying from 89,889 Chantix users. Check the latest studies of Chantix.

What is Rabeprazole?

Rabeprazole has active ingredients of rabeprazole sodium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 31,689 Rabeprazole users. Check the latest studies of Rabeprazole.

On Aug, 06, 2026

22 people who take Chantix and Rabeprazole together, and have interactions are studied.

Chantix and Rabeprazole drug interactions.

What are the common drug interactions of Chantix and Rabeprazole, by gender? *:

female:

Blood glucose increased
Chest discomfort
Constipation
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Headache (pain in head)
Hypersensitivity
Lip swelling
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)

male:

Anorexia (eating disorder characterized by immoderate food restriction and irrational fear of gaining weight)
Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
Disturbance in attention
Dyspnoea (difficult or laboured respiration)
Headache (pain in head)
Neck pain
Parosmia (distortion of the sense of smell, as in smelling odours that are not present)
Sleep disorder
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Blast cell count increased

What are the common drug interactions of Chantix and Rabeprazole, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Headache (pain in head)

30-39:

n/a

40-49:

Chest discomfort
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Hypersensitivity
Lip swelling
Malaise (a feeling of general discomfort or uneasiness)
Pyrexia (fever)
Swelling face
Abdominal discomfort
Abdominal distension

50-59:

Constipation
Haemodynamic instability (disturbances in the blood movement in our body)
Muscular weakness (muscle weakness)
Pericardial effusion (fluid around the heart)
Pleural effusion (water on the lungs)
Post procedural infection
Procedural complication
Pulmonary oedema (fluid accumulation in the lungs)
Respiratory distress (difficulty in breathing)
Weight decreased

60+:

Drug hypersensitivity
Blast cell count increased
Neutropenia (an abnormally low number of neutrophils)
Platelet count decreased
Pneumonia

What are the existing conditions these people have? *

Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 2 people, 9.09%
Diabetes: 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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