Chestnut and Clonazepam drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chestnut (horse chestnut) and Clonazepam (clonazepam). Common drug interactions include coma among females and constipation among males.

The phase IV clinical study analyzes what interactions people have when they take Chestnut and Clonazepam. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.

What is Chestnut?

Chestnut has active ingredients of horse chestnut. eHealthMe is studying from 538 Chestnut users. Check the latest studies of Chestnut.

What is Clonazepam?

Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,270 Clonazepam users. Check the latest studies of Clonazepam.

On Jul, 30, 2026

14 people who take Chestnut and Clonazepam together, and have interactions are studied.

Chestnut and Clonazepam drug interactions.

What are the common drug interactions of Chestnut and Clonazepam, by gender? *:

female:

Coma (state of unconsciousness lasting more than six hours)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Somnolence (a state of near-sleep, a strong desire for sleep)
Chronic kidney disease
Dental caries
Renal failure (kidney dysfunction)
Renal tubular necrosis (death of kidney tubules)
Tooth loss

male:

Constipation
Depression
Tinnitus (a ringing in the ears)
Tremor (trembling or shaking movements in one or more parts of your body)
Weight increased
Fatigue (feeling of tiredness)
Drug ineffective
Urinary tract infection
Dizziness
Dry mouth

What are the common drug interactions of Chestnut and Clonazepam, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Dental caries
Tooth loss

40-49:

n/a

50-59:

Muscular weakness (muscle weakness)
Nausea (feeling of having an urge to vomit)
Somnolence (a state of near-sleep, a strong desire for sleep)
Suicidal ideation
Tinnitus (a ringing in the ears)
Tremor (trembling or shaking movements in one or more parts of your body)
Weight increased
Fatigue (feeling of tiredness)
Chronic kidney disease
Drug ineffective

60+:

Coma (state of unconsciousness lasting more than six hours)
Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
Pneumonia aspiration (bronchopneumonia that develops due to the entrance of foreign materials into the bronchial tree)
Somnolence (a state of near-sleep, a strong desire for sleep)

What are the existing conditions these people have? *

Pain: 2 people, 14.29%
Depression: 2 people, 14.29%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 2 people, 14.29%
Swelling: 1 person, 7.14%
High Blood Pressure: 1 person, 7.14%
Asthma: 1 person, 7.14%
Blood Potassium Decreased: 1 person, 7.14%
Cardiac Disorder: 1 person, 7.14%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 1 person, 7.14%
Diabetes: 1 person, 7.14%

* Approximation only. Some reports may have incomplete information.

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