Chestnut and Flaxseed drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Chestnut (horse chestnut) and Flaxseed (flaxseed). Common drug interactions include angiopathy among females and appendicitis among males.
The phase IV clinical study analyzes what interactions people have when they take Chestnut and Flaxseed. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.
What is Chestnut?
Chestnut has active ingredients of horse chestnut. eHealthMe is studying from 538 Chestnut users. Check the latest studies of Chestnut.
What is Flaxseed?
Flaxseed has active ingredients of flaxseed. It is often used in high blood cholesterol. eHealthMe is studying from 7,137 Flaxseed users. Check the latest studies of Flaxseed.
15 people who take Chestnut and Flaxseed together, and have interactions are studied.

What are the common drug interactions of Chestnut and Flaxseed, by gender? *:
female:
- Angiopathy (generic term for a disease of the blood vessels)
- Arthralgia (joint pain)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
- Constipation
- Fall
- Femur fracture
- Fracture nonunion (permanent failure of healing following a broken bone)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
male:
- Appendicitis (inflammation of the appendix)
- Viral load increased
- General physical health deterioration (weak health status)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Myasthenia gravis (a chronic condition that causes muscles to tire and weaken easily)
- Nausea (feeling of having an urge to vomit)
- Sepsis (a severe blood infection that can lead to organ failure and death)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Stress
- Ventricular fibrillation (abnormally irregular heart rhythm)
What are the common drug interactions of Chestnut and Flaxseed, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Viral load increased
- Appendicitis (inflammation of the appendix)
20-29:
n/a
30-39:
n/a
40-49:
- Angiopathy (generic term for a disease of the blood vessels)
- Arthralgia (joint pain)
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cervical dysplasia (abnormal changes in the cells on the surface of the cervix)
- Constipation
- Fall
- Femur fracture
- Fracture nonunion (permanent failure of healing following a broken bone)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
50-59:
n/a
60+:
- Constipation
- Angiopathy (generic term for a disease of the blood vessels)
- Fracture nonunion (permanent failure of healing following a broken bone)
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Intraductal papilloma of breast (tiny wart-like growth in breast tissue)
- Metaplasia (change in the type of adult cells in a tissue to a form abnormal for that tissue)
- Neuropathy peripheral (surface nerve damage)
- Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Osteoporosis (bones weak and more likely to break)
What are the existing conditions these people have? *
- High Blood Pressure: 5 people, 33.33%
- Herpes Simplex (herpes simplex is a common viral infection): 5 people, 33.33%
- Osteopenia (a condition where bone mineral density is lower than normal): 5 people, 33.33%
- Haemorrhoids (a swollen vein or group of veins in the region of the anus): 3 people, 20.00%
- Hiv Infection: 3 people, 20.00%
- Diabetes: 2 people, 13.33%
- Eye Disorder: 1 person, 6.67%
- Enlarged Prostate: 1 person, 6.67%
- Dyspnea (difficult or laboured breathing): 1 person, 6.67%
- Drowsiness: 1 person, 6.67%
* Approximation only. Some reports may have incomplete information.
Do you take Chestnut and Flaxseed?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Chestnut and Flaxseed:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Chestnut:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Flaxseed:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Chestnut and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flaxseed and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on horse chestnut and flaxseed (the active ingredients of Chestnut and Flaxseed, respectively), and Chestnut and Flaxseed (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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