Chlor-trimeton and Clonazepam drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Chlor-trimeton (chlorpheniramine maleate) and Clonazepam (clonazepam). Common drug interactions include dyspepsia among females and completed suicide among males.
The phase IV clinical study analyzes what interactions people have when they take Chlor-trimeton and Clonazepam. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.
What is Chlor-trimeton?
Chlor-trimeton has active ingredients of chlorpheniramine maleate. It is often used in allergies. eHealthMe is studying from 1,472 Chlor-trimeton users. Check the latest studies of Chlor-trimeton.
What is Clonazepam?
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,270 Clonazepam users. Check the latest studies of Clonazepam.
13 people who take Chlor-trimeton and Clonazepam together, and have interactions are studied.

What are the common drug interactions of Chlor-Trimeton and Clonazepam, by gender? *:
female:
- Dyspepsia (indigestion)
- Feeling drunk
- Impaired driving ability
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
- Hot flush (sudden feelings of heat)
- Migraine (headache)
- Peripheral coldness
- Tinnitus (a ringing in the ears)
- Acne (skin problems that cause pimples)
- Chest discomfort
male:
- Completed suicide (act of taking one's own life)
- Disease progression
- Drug abuse
- Dyspnoea (difficult or laboured respiration)
- Renal cell carcinoma (a kidney cancer)
- Back pain
What are the common drug interactions of Chlor-Trimeton and Clonazepam, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Drug abuse
30-39:
- Completed suicide (act of taking one's own life)
- Disease progression
- Dyspnoea (difficult or laboured respiration)
- Renal cell carcinoma (a kidney cancer)
- Hot flush (sudden feelings of heat)
- Migraine (headache)
- Peripheral coldness
- Tinnitus (a ringing in the ears)
40-49:
- Surgery
50-59:
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Disturbance in attention
- Dizziness
- Dyspepsia (indigestion)
- Feeling drunk
- Impaired driving ability
- Movement disorder (neurological syndromes where they may be excess of movement or a paucity of movement that is not connected to weakness)
- Vision blurred
- Back pain
- Diarrhoea
60+:
- Acne (skin problems that cause pimples)
- Constipation
- Neutropenic infection (infection with less neutrophil numbers in blood)
- Paronychia (infection in the tissues adjacent to a nail on a finger or toe)
- Vision blurred
- Dry skin
- Dysgeusia (disorder of the sense of taste)
- Erythema (redness of the skin)
- Feeling hot
- Hypokalaemia (low potassium)
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 23.08%
- Ill-Defined Disorder: 2 people, 15.38%
- High Blood Pressure: 2 people, 15.38%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 2 people, 15.38%
- Renal Cell Carcinoma (a kidney cancer): 1 person, 7.69%
- Rectal Cancer (cancer of rectum): 1 person, 7.69%
- Pain: 1 person, 7.69%
- Neuralgia (pain in one or more nerves): 1 person, 7.69%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 7.69%
- Hypersensitivity: 1 person, 7.69%
* Approximation only. Some reports may have incomplete information.
Do you take Chlor-trimeton and Clonazepam?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Chlor-trimeton (1,472 reports)
- Clonazepam (146,270 reports)
Browse all drug interactions of Chlor-trimeton and Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Chlor-trimeton:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Chlor-trimeton and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clonazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on chlorpheniramine maleate and clonazepam (the active ingredients of Chlor-trimeton and Clonazepam, respectively), and Chlor-trimeton and Clonazepam (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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