Chloramphenicol and Valacyclovir drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chloramphenicol (chloramphenicol) and Valacyclovir (valacyclovir hydrochloride). Common drug interactions include pyrexia among females and febrile neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Chloramphenicol and Valacyclovir. It is created by eHealthMe based on reports of 33 people who take the same drugs from the FDA, and is updated regularly.

What is Chloramphenicol?

Chloramphenicol has active ingredients of chloramphenicol. eHealthMe is studying from 2,581 Chloramphenicol users. Check the latest studies of Chloramphenicol.

What is Valacyclovir?

Valacyclovir has active ingredients of valacyclovir hydrochloride. It is often used in genital herpes. eHealthMe is studying from 42,108 Valacyclovir users. Check the latest studies of Valacyclovir.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Sep, 04, 2026

33 people who take Chloramphenicol and Valacyclovir together, and have interactions are studied.

Chloramphenicol and Valacyclovir drug interactions.

What are the common drug interactions of Chloramphenicol and Valacyclovir, by gender? *:

female:

  1. Pyrexia (fever)
  2. Chills (felling of cold)
  3. Hyperhidrosis (abnormally increased sweating)
  4. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  5. Vomiting
  6. Cystoid macular oedema (fluid accumulation after cataract surgery)
  7. Cardiac arrest
  8. Cytokine release syndrome (immediate complication occurring with the use of anti-t cell antibody infusions)
  9. Hypersomnia (excessive daytime sleepiness (eds))
  10. Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)

male:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
  3. Facial paralysis (loss of function of face muscle)
  4. Lower respiratory tract infection
  5. Metastatic renal cell carcinoma (spreadable kidney cell tumour)
  6. Psoriasis (immune-mediated disease that affects the skin)
  7. Bowen's disease (early stage of skin cancer)
  8. Keratopathy (noninflammatory disease of the cornea)
  9. Septic shock (shock due to blood infection)
  10. Skin mass

What are the common drug interactions of Chloramphenicol and Valacyclovir, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Asthma

20-29:

n/a

30-39:

n/a

40-49:

  1. Chills (felling of cold)
  2. Hyperhidrosis (abnormally increased sweating)
  3. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  4. Pyrexia (fever)
  5. Vomiting

50-59:

  1. Febrile neutropenia (fever with reduced white blood cells)
  2. Septic shock (shock due to blood infection)
  3. Pneumonia
  4. Pyrexia (fever)

60+:

  1. Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
  2. Bowen's disease (early stage of skin cancer)
  3. Facial paralysis (loss of function of face muscle)
  4. Febrile neutropenia (fever with reduced white blood cells)
  5. Hypersomnia (excessive daytime sleepiness (eds))
  6. Lower respiratory tract infection
  7. Metastatic renal cell carcinoma (spreadable kidney cell tumour)
  8. Parkinsonism (degenerative disorder of the central nervous system characterized by tremor and impaired muscular coordination)
  9. Psoriasis (immune-mediated disease that affects the skin)
  10. Cystoid macular oedema (fluid accumulation after cataract surgery)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 19 people, 57.58%
  2. Conjunctivitis (pink eye): 12 people, 36.36%
  3. Nausea (feeling of having an urge to vomit): 11 people, 33.33%
  4. Fever: 9 people, 27.27%
  5. Back Pain: 8 people, 24.24%
  6. Diarrhea: 6 people, 18.18%
  7. Joint Pain: 5 people, 15.15%
  8. Electrolyte Imbalance: 5 people, 15.15%
  9. Neutrophil Count Decreased (less than normal number of neutrophil a type of blood cell): 5 people, 15.15%
  10. Ocular Hyperaemia (an abnormally large amount of blood in eye): 5 people, 15.15%

* Approximation only. Some reports may have incomplete information.

Do you take Chloramphenicol and Valacyclovir?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Chloramphenicol and Valacyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Chloramphenicol:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Valacyclovir:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Chloramphenicol and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Valacyclovir and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on chloramphenicol and valacyclovir hydrochloride (the active ingredients of Chloramphenicol and Valacyclovir, respectively), and Chloramphenicol and Valacyclovir (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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