Chlorhexidine gluconate and Cisplatin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chlorhexidine gluconate (chlorhexidine gluconate) and Cisplatin (cisplatin). Common drug interactions include pain among females and neutropenia among males.

The phase IV clinical study analyzes what interactions people have when they take Chlorhexidine gluconate and Cisplatin. It is created by eHealthMe based on reports of 48 people who take the same drugs from the FDA, and is updated regularly.

What is Chlorhexidine gluconate?

Chlorhexidine gluconate has active ingredients of chlorhexidine gluconate. eHealthMe is studying from 8,233 Chlorhexidine gluconate users. Check the latest studies of Chlorhexidine gluconate.

What is Cisplatin?

Cisplatin has active ingredients of cisplatin. It is often used in chemotherapy. eHealthMe is studying from 92,837 Cisplatin users. Check the latest studies of Cisplatin.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Aug, 24, 2026

48 people who take Chlorhexidine gluconate and Cisplatin together, and have interactions are studied.

Chlorhexidine gluconate and Cisplatin drug interactions.

What are the common drug interactions of Chlorhexidine Gluconate and Cisplatin, by gender? *:

female:

Pain
Arthralgia (joint pain)
Dyspnoea (difficult or laboured respiration)
Neuropathy peripheral (surface nerve damage)
Pneumonia
Staphylococcal bacteraemia (a bacterial infection of blood)
Acute sinusitis
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Aortic valve incompetence
Bone disorder

male:

Neutropenia (an abnormally low number of neutrophils)
Thrombocytopenia (decrease of platelets in blood)
Pneumonia
Pulmonary embolism (blockage of the main artery of the lung)
Abdominal distension
Apathy
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)

What are the common drug interactions of Chlorhexidine Gluconate and Cisplatin, by age (0-1 to 60+)? *:

0-1:

Abdominal distension
Alopecia (absence of hair from areas of the body)
Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
Candidiasis (candidiasis or thrush is a fungal infection)
Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
Failure to thrive (inadequate weight gain and physical growth in children)
Fluid overload (too much fluid in the blood)
Gastroenteritis (inflammation of stomach and intestine)
Hypertension (high blood pressure)
Hypotension (abnormally low blood pressure)

2-9:

n/a

10-19:

n/a

20-29:

Cardiac arrest
Sudden death

30-39:

Diarrhoea
Ileus (a painful obstruction of the ileum or other part of the intestine)
Vomiting
Anxiety
Depression
Drug ineffective
Renal failure acute (rapid kidney dysfunction)
Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)
Pulmonary embolism (blockage of the main artery of the lung)
Acute respiratory distress syndrome

40-49:

Insomnia (sleeplessness)
Apathy
Arthralgia (joint pain)
Arthritis (form of joint disorder that involves inflammation of one or more joints)
Astigmatism (refractive error of the eye in which parallel rays of light from an external source do not converge on a single focal point on the retina)
Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
Depression
Dermatitis atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder)
Device related infection
Dry eye (lack of adequate tears)

50-59:

Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Herpes zoster
Pericardial effusion (fluid around the heart)
Pulmonary embolism (blockage of the main artery of the lung)
Rash pustular (redness with pustules)
Weight decreased
Alanine aminotransferase increased
Aortic embolus (obstruction of aortic artery)
Arteriosclerosis (thickening and hardening of arteries)
Asthenia (weakness)

60+:

Mucosal inflammation (infection of mucous membrane)
Dysphagia (a condition in which swallowing is difficult or painful)
Disease progression
Diverticulum intestinal (a pouch that is attached to the first part of the small intestine)
Dyspnoea (difficult or laboured respiration)
Emotional distress
Endocarditis (inflammation in heart muscle)
Fall
Foot fracture
Haemorrhoids (a swollen vein or group of veins in the region of the anus)

What are the existing conditions these people have? *

Cough: 8 people, 16.67%
Multiple Myeloma (cancer of the plasma cells): 8 people, 16.67%
Lung Cancer - Non-Small Cell (lung cancer): 7 people, 14.58%
Neoplasm Malignant (cancer tumour): 7 people, 14.58%
Constipation: 6 people, 12.50%
Nausea (feeling of having an urge to vomit): 5 people, 10.42%
Oral Cancer (mouth cancer): 5 people, 10.42%
Appetite - Decreased (decreased appetite occurs when you have a reduced desire to eat): 5 people, 10.42%
Pain: 4 people, 8.33%
Fever: 4 people, 8.33%

* Approximation only. Some reports may have incomplete information.

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