Chlorothiazide and Flovent drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Chlorothiazide (chlorothiazide) and Flovent (fluticasone propionate). Common drug interactions include acute respiratory failure among females and infusion site mass among males.
The phase IV clinical study analyzes what interactions people have when they take Chlorothiazide and Flovent. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.
What is Chlorothiazide?
Chlorothiazide has active ingredients of chlorothiazide. eHealthMe is studying from 1,220 Chlorothiazide users. Check the latest studies of Chlorothiazide.
What is Flovent?
Flovent has active ingredients of fluticasone propionate. It is often used in asthma. eHealthMe is studying from 44,817 Flovent users. Check the latest studies of Flovent.
36 people who take Chlorothiazide and Flovent together, and have interactions are studied.

What are the common drug interactions of Chlorothiazide and Flovent, by gender? *:
female:
- Acute respiratory failure
- Arthralgia (joint pain)
- Back pain
- Drug ineffective
- Dyspnoea (difficult or laboured respiration)
- Hypertension (high blood pressure)
- Hypervolaemia (abnormally increased volume of blood)
- Renal failure (kidney dysfunction)
- Respiratory syncytial virus infection (viral disease of respiratory system)
- Abdominal pain
male:
- Infusion site mass
- Cryptorchism
- Respiratory disorder (respiratory disease)
- Gastroenteritis viral (inflammation of stomach and intestine caused by virus infection)
- Respiratory syncytial virus infection (viral disease of respiratory system)
- Pneumonia
- Tracheitis (an inflammation of the trachea)
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
- Lipoma (a growth of fatty tissue that slowly develops just under your skin)
- Arthralgia (joint pain)
What are the common drug interactions of Chlorothiazide and Flovent, by age (0-1 to 60+)? *:
0-1:
- Respiratory syncytial virus infection (viral disease of respiratory system)
- Acute respiratory failure
- Atelectasis (partial or complete collapse of the lung)
- Dyspnoea (difficult or laboured respiration)
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
2-9:
- Infusion site erythema (reddening of the skin at infusion site)
- Infusion site induration
- Infusion site infection
- Localised infection (infection at the single location)
10-19:
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
- Lipoma (a growth of fatty tissue that slowly develops just under your skin)
- Infective pulmonary exacerbation of cystic fibrosis (severe infective lung disease with production of abnormally thick mucus)
- Respiratory failure (inadequate gas exchange by the respiratory system)
20-29:
- Hernia (hernia happens when part of an internal organ or tissue bulges through a weak area of muscle)
- Loss of consciousness
- Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
- Tracheostomy infection (infection of trachea surgical opening)
- Pyrexia (fever)
- Respiratory disorder (respiratory disease)
- Pneumonia
30-39:
- Abdominal pain
- Biliary colic
- Biliary dyskinesia (motility disorder that affects the gallbladder and sphincter of oddi)
- Cholecystitis (infection of gallbladder)
- Nausea (feeling of having an urge to vomit)
40-49:
n/a
50-59:
- Arthralgia (joint pain)
- Back pain
- Drug ineffective
- Hypertension (high blood pressure)
- Arrhythmia (irregular heartbeat)
- Atrioventricular block (heart block)
- Candidiasis (candidiasis or thrush is a fungal infection)
- Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
- Chronic kidney disease
- Ischaemic cardiomyopathy (weakness in the muscle of the heart due to inadequate oxygen delivery to the myocardium with coronary artery disease)
60+:
- Acute respiratory failure
- Hypervolaemia (abnormally increased volume of blood)
- Glomerular filtration rate decreased
- Hypoglycaemia (deficiency of glucose in the bloodstream)
- Hypotension (abnormally low blood pressure)
- Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
- Metabolic encephalopathy (disorder or disease of the brain due to the body's disability to use energy)
- Nausea (feeling of having an urge to vomit)
- Pruritus generalised (generalized itching)
- Rash generalised (rash on most of body parts)
What are the existing conditions these people have? *
- Infection: 7 people, 19.44%
- Immunodeficiency Common Variable: 7 people, 19.44%
- Pulmonary Hypertension (increase in blood pressure in the lung artery): 5 people, 13.89%
- Primary Pulmonary Hypertension (primary high blood pressure that affects the arteries in the lungs and the right side of your heart): 3 people, 8.33%
- Premature Baby: 3 people, 8.33%
- High Blood Pressure: 3 people, 8.33%
- Pain: 2 people, 5.56%
- High Blood Cholesterol: 2 people, 5.56%
- Cystic Fibrosis (disease of the secretary glands): 2 people, 5.56%
* Approximation only. Some reports may have incomplete information.
Do you take Chlorothiazide and Flovent?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Chlorothiazide (1,220 reports)
- Flovent (44,817 reports)
Browse all drug interactions of Chlorothiazide and Flovent:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Chlorothiazide:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Flovent:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Chlorothiazide and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Flovent and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
- Lehrer, S., & Rheinstein, P. H. , "Alzheimer’s Disease and Intranasal Fluticasone Propionate in the FDA MedWatch Adverse Events Database", Journal of Alzheimer's disease reports, (Preprint), 1-5., 2018 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on chlorothiazide and fluticasone propionate (the active ingredients of Chlorothiazide and Flovent, respectively), and Chlorothiazide and Flovent (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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