Chlorpheniramine maleate and Hydrocortisone acetate drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chlorpheniramine maleate (chlorpheniramine maleate) and Hydrocortisone acetate (hydrocortisone acetate). Common drug interactions include bronchospasm among females and vomiting among males.

The phase IV clinical study analyzes what interactions people have when they take Chlorpheniramine maleate and Hydrocortisone acetate. It is created by eHealthMe based on reports of 37 people who take the same drugs from the FDA, and is updated regularly.

What is Chlorpheniramine maleate?

Chlorpheniramine maleate has active ingredients of chlorpheniramine maleate. It is often used in allergies. eHealthMe is studying from 7,632 Chlorpheniramine maleate users. Check the latest studies of Chlorpheniramine maleate.

What is Hydrocortisone acetate?

Hydrocortisone acetate has active ingredients of hydrocortisone acetate. It is often used in ulcerative colitis. eHealthMe is studying from 4,344 Hydrocortisone acetate users. Check the latest studies of Hydrocortisone acetate.

On Jul, 07, 2026

37 people who take Chlorpheniramine maleate and Hydrocortisone acetate together, and have interactions are studied.

Chlorpheniramine maleate and Hydrocortisone acetate drug interactions.

What are the common drug interactions of Chlorpheniramine Maleate and Hydrocortisone Acetate, by gender? *:

female:

Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)
Erythema (redness of the skin)
Swelling face
Diarrhoea

male:

Vomiting
Drug hypersensitivity
Constipation
Bacterial infection
Nausea (feeling of having an urge to vomit)
Blood cholesterol increased
Anaemia (lack of blood)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug intolerance (drug sensitivity)
Dyspnoea (difficult or laboured respiration)

What are the common drug interactions of Chlorpheniramine Maleate and Hydrocortisone Acetate, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Hypothermia (body temperature drops below the required temperature for normal metabolism and body functions)
Malaise (a feeling of general discomfort or uneasiness)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Blood sodium decreased
Brain neoplasm (tumour of brain)
Memory impairment
Vomiting
Death
Diabetes insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function)
Pneumonia

40-49:

Palmar erythema (reddening of the palms at the thenar and hypothenar eminences)

50-59:

n/a

60+:

Drug hypersensitivity
Neuralgia (pain in one or more nerves)
Bacterial infection
Nausea (feeling of having an urge to vomit)
Blood cholesterol increased
Anaemia (lack of blood)
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Drug intolerance (drug sensitivity)
Dyspnoea (difficult or laboured respiration)
Pulmonary embolism (blockage of the main artery of the lung)

What are the existing conditions these people have? *

Constipation: 23 people, 62.16%
High Blood Cholesterol: 19 people, 51.35%
Iron Deficiency: 19 people, 51.35%
Bacterial Infection: 19 people, 51.35%
Blood Phosphorus Increased: 19 people, 51.35%
Blood Uric Acid Increased: 19 people, 51.35%
Cardiogenic Shock (inadequate circulation of blood): 19 people, 51.35%
Chronic Obstructive Pulmonary Disease (a progressive disease that makes it hard to breathe): 19 people, 51.35%
Diabetes: 19 people, 51.35%
Dyspnea (difficult or laboured breathing): 19 people, 51.35%

* Approximation only. Some reports may have incomplete information.

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