Loraz and Nipride drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Loraz (lorazepam) and Nipride (sodium nitroprusside). Common drug interactions include gastrooesophageal reflux disease among females and hypertension among males.
The phase IV clinical study analyzes what interactions people have when they take Loraz and Nipride. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Loraz?
Loraz has active ingredients of lorazepam. It is often used in stress and anxiety. eHealthMe is studying from 165,694 Loraz users. Check the latest studies of Loraz.
What is Nipride?
Nipride has active ingredients of sodium nitroprusside. eHealthMe is studying from 313 Nipride users. Check the latest studies of Nipride.
16 people who take Loraz and Nipride together, and have interactions are studied.

What are the common drug interactions of Loraz and Nipride, by gender? *:
female:
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Injury
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
- Osteopenia (a condition where bone mineral density is lower than normal)
- Pain in jaw
- Pathological fracture (broken bone caused by disease)
- Renal cyst (kidney cyst)
- Urinary tract infection
- Acquired porphyria (group of disorders that result in a build up of chemicals called porphyrins in the body)
- Aplastic anaemia (blood disorder in which the body's bone marrow doesn't make enough new blood cells)
male:
- Hypertension (high blood pressure)
- Atelectasis (partial or complete collapse of the lung)
- Neutropenic infection (infection with less neutrophil numbers in blood)
- Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
- Platelet count decreased
- Pleural effusion (water on the lungs)
- Posterior reversible encephalopathy syndrome (posterior reversible encephalopathy syndrome (pres), also known as reversible posterior leukoencephalopathy syndrome (rpls), is a syndrome characterized by headache, confusion, seizures and visual loss)
- Sinusitis (inflammation of sinus)
- Wheezing (a high-pitched whistling sound made while you breath)
- Injury
What are the common drug interactions of Loraz and Nipride, by age (0-1 to 60+)? *:
0-1:
- Death
- Injury
- Pain
- Renal failure (kidney dysfunction)
- Renal failure acute (rapid kidney dysfunction)
- Renal injury (kidney injury)
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Death
- Emotional distress
- Fear
- Injury
- Pain
- Renal failure (kidney dysfunction)
- Renal injury (kidney injury)
- Renal failure acute (rapid kidney dysfunction)
- Renal impairment (severely reduced kidney function)
50-59:
- Blood glucose increased
- Bone disorder
- Bone fragmentation
- Bone marrow granuloma (collection of inflammatory cells in bone marrow)
- Breast cancer recurrent
- Carpal tunnel syndrome (nerve compression at wrist results numbness weakness, pain , swelling)
- Central nervous system lymphoma (cancer of central nervous system forms in lymph tissue)
- Cholangitis chronic (long lasting infection of the bile duct)
- Cholecystitis acute (rapid infection of gallbladder)
- Circulatory collapse
60+:
- Acquired porphyria (group of disorders that result in a build up of chemicals called porphyrins in the body)
- Anaemia (lack of blood)
- Colitis (inflammation of colon)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Costochondritis (chest wall pain)
- Device related infection
- Diarrhoea
- Disability
- Electrolyte imbalance
- Encephalitis post measles (inflammation of the brain- post measles infection)
What are the existing conditions these people have? *
- Multiple Sclerosis (a nervous system disease that affects your brain and spinal cord. it damages the myelin sheath): 2 people, 12.50%
- Multiple Allergies (allergy to multiple agents): 2 people, 12.50%
- High Blood Pressure: 2 people, 12.50%
- Quit Smoking: 1 person, 6.25%
- Pain: 1 person, 6.25%
- Metastases To Bone (cancer spreads to bone): 1 person, 6.25%
- Endometrial Cancer: 1 person, 6.25%
- Diabetes: 1 person, 6.25%
* Approximation only. Some reports may have incomplete information.
Do you take Loraz and Nipride?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Loraz and Nipride:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Loraz:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Nipride:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Loraz and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Nipride and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on lorazepam and sodium nitroprusside (the active ingredients of Loraz and Nipride, respectively), and Loraz and Nipride (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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