Cholestyramine light and Nexium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cholestyramine light (cholestyramine) and Nexium (esomeprazole magnesium). Common drug interactions include cystitis among females and anhedonia among males.

The phase IV clinical study analyzes what interactions people have when they take Cholestyramine light and Nexium. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Cholestyramine light?

Cholestyramine light has active ingredients of cholestyramine. It is often used in high blood cholesterol. eHealthMe is studying from 297 Cholestyramine light users. Check the latest studies of Cholestyramine light.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,678 Nexium users. Check the latest studies of Nexium.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.



On Aug, 22, 2026

13 people who take Cholestyramine light and Nexium together, and have interactions are studied.

Cholestyramine light and Nexium drug interactions.

What are the common drug interactions of Cholestyramine Light and Nexium, by gender? *:

female:

  1. Cystitis (inflammation of the wall of the bladder)
  2. Muscle spasms (muscle contraction)
  3. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  4. Urticaria (rash of round, red welts on the skin that itch intensely)
  5. Weight increased
  6. Abdominal pain
  7. Acute sinusitis
  8. Alopecia (absence of hair from areas of the body)
  9. Anaemia (lack of blood)
  10. Angioedema (rapid swelling of the dermis)

male:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Bone density decreased
  4. Emotional distress
  5. Hand fracture
  6. Hospitalisation
  7. Jaw fracture
  8. Pain
  9. Platelet count decreased

What are the common drug interactions of Cholestyramine Light and Nexium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  2. Anxiety
  3. Bone density decreased
  4. Emotional distress
  5. Hand fracture
  6. Jaw fracture
  7. Pain

40-49:

  1. Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

50-59:

  1. Abdominal pain
  2. Acute sinusitis
  3. Alopecia (absence of hair from areas of the body)
  4. Anaemia (lack of blood)
  5. Arthropathy
  6. Asthma
  7. Blood alkaline phosphatase increased
  8. Breast mass
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Bronchospasm (spasm of bronchial smooth muscle producing narrowing of the bronchi)

60+:

  1. Chronic kidney disease
  2. Muscle spasms (muscle contraction)
  3. Malaise (a feeling of general discomfort or uneasiness)
  4. Platelet count decreased
  5. Urinary retention (the inability to completely or partially empty the bladder)
  6. Urticaria (rash of round, red welts on the skin that itch intensely)
  7. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  8. Angioedema (rapid swelling of the dermis)
  9. Cataract (clouding of the lens inside the eye)
  10. Chills (felling of cold)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 3 people, 23.08%
  2. Osteoporosis Post-Menopausal (weak bone with possibility to break after stopped menstrual cycles): 2 people, 15.38%
  3. Crohn's Disease (a condition that causes inflammation of the gastrointestinal tract): 2 people, 15.38%
  4. Inflammation: 2 people, 15.38%
  5. Nausea (feeling of having an urge to vomit): 2 people, 15.38%
  6. Fungal Infection: 2 people, 15.38%
  7. Stress And Anxiety: 2 people, 15.38%
  8. Sleep Disorder: 2 people, 15.38%
  9. Chest Pain: 2 people, 15.38%
  10. Depression: 2 people, 15.38%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cholestyramine light and Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cholestyramine light:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cholestyramine light and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nexium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on cholestyramine and esomeprazole magnesium (the active ingredients of Cholestyramine light and Nexium, respectively), and Cholestyramine light and Nexium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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