Cholestyramine and Zemplar drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cholestyramine (cholestyramine) and Zemplar (paricalcitol). Common drug interactions include nephrogenic systemic fibrosis among females and oedema peripheral among males.

The phase IV clinical study analyzes what interactions people have when they take Cholestyramine and Zemplar. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Cholestyramine?

Cholestyramine has active ingredients of cholestyramine. It is often used in diarrhea. eHealthMe is studying from 9,893 Cholestyramine users. Check the latest studies of Cholestyramine.

What is Zemplar?

Zemplar has active ingredients of paricalcitol. It is often used in kidney disease. eHealthMe is studying from 15,494 Zemplar users. Check the latest studies of Zemplar.

On Jul, 26, 2026

22 people who take Cholestyramine and Zemplar together, and have interactions are studied.

Cholestyramine and Zemplar drug interactions.

What are the common drug interactions of Cholestyramine and Zemplar, by gender? *:

female:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)
Burning sensation
Chest pain
Drug hypersensitivity
Dyskinesia (abnormality or impairment of voluntary movement)
Dyspnoea (difficult or laboured respiration)
Electrocardiogram t wave inversion
Erythema (redness of the skin)
Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
Hypokalaemia (low potassium)

male:

Oedema peripheral (superficial swelling)
Abscess jaw (tooth abscess or root abscess)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bacteraemia (presence of bacteria in the blood)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Bicytopenia (two parameters from the full blood count are low, the term bicytopenia can be used)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Calcium metabolism disorder (occur when the body has too little or too much calcium)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)

What are the common drug interactions of Cholestyramine and Zemplar, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Renal transplant

30-39:

n/a

40-49:

Nephrogenic systemic fibrosis (involves fibrosis of skin, joints, eyes due to kidney disease)

50-59:

Chronic kidney disease
Drug hypersensitivity
Dyskinesia (abnormality or impairment of voluntary movement)
Dyspnoea (difficult or laboured respiration)
Electrocardiogram t wave inversion
Erythema (redness of the skin)
Hypokalaemia (low potassium)
Hypotension (abnormally low blood pressure)
Lip swelling
Slow response to stimuli (slow response by nerves)

60+:

Nephrogenic anaemia (anaemia due to kidney disease)
Abscess jaw (tooth abscess or root abscess)
Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
Bacteraemia (presence of bacteria in the blood)
Benign prostatic hyperplasia (benign enlargement of the prostate)
Bicytopenia (two parameters from the full blood count are low, the term bicytopenia can be used)
Bundle branch block right (absence of transmission of electric impulses from the atrioventricular (av) bundle of his to the right ventricle)
Calcium metabolism disorder (occur when the body has too little or too much calcium)
Cardiac failure congestive
Cardiomegaly (increased size of heart than normal)

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 8 people, 36.36%
Pain: 5 people, 22.73%
High Blood Pressure: 4 people, 18.18%
High Blood Cholesterol: 4 people, 18.18%
Swelling: 3 people, 13.64%
Infection: 3 people, 13.64%
Fluid Retention (an abnormal accumulation of fluid in the blood): 3 people, 13.64%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 3 people, 13.64%
Headache (pain in head): 2 people, 9.09%
Chronic Renal Failure (kidney failure): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

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