Chromium picolinate and Vitamin e drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Chromium picolinate (chromium) and Vitamin e (tocopherols and tocotrienols). Common drug interactions include abdominal pain among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Chromium picolinate and Vitamin e. It is created by eHealthMe based on reports of 85 people who take the same drugs from the FDA, and is updated regularly.

What is Chromium picolinate?

Chromium picolinate has active ingredients of chromium. It is often used in weight loss. eHealthMe is studying from 1,205 Chromium picolinate users. Check the latest studies of Chromium picolinate.

What is Vitamin e?

Vitamin e has active ingredients of tocopherols and tocotrienols. It is often used in vitamin supplementation. eHealthMe is studying from 42,279 Vitamin e users. Check the latest studies of Vitamin e.



On Jul, 30, 2026

85 people who take Chromium picolinate and Vitamin e together, and have interactions are studied.

Chromium picolinate and Vitamin e drug interactions.

What are the common drug interactions of Chromium Picolinate and Vitamin E, by gender? *:

female:

  1. Abdominal pain
  2. Balance disorder
  3. Body height decreased
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Chest discomfort
  6. Chills (felling of cold)
  7. Chronic kidney disease
  8. Erythema (redness of the skin)
  9. Hot flush (sudden feelings of heat)
  10. Hypertension (high blood pressure)

male:

  1. Chronic kidney disease
  2. Diarrhoea
  3. Groin abscess (pus in groin)
  4. Hospitalisation
  5. Hyperkeratosis (thickening of the outer layer of the skin)
  6. Hypertension (high blood pressure)
  7. Hypotension (abnormally low blood pressure)
  8. Nasal dryness (dry nose)
  9. Necrotising fasciitis (an uncommon life-threatening soft-tissue infection)
  10. Pain

What are the common drug interactions of Chromium Picolinate and Vitamin E, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Burning sensation
  2. Hallucination (an experience involving the perception of something not present)
  3. Myalgia (muscle pain)
  4. Neuralgia (pain in one or more nerves)
  5. Somnolence (a state of near-sleep, a strong desire for sleep)

30-39:

n/a

40-49:

  1. Anxiety
  2. Chronic kidney disease
  3. Dizziness
  4. Emotional distress
  5. Fatigue (feeling of tiredness)
  6. Nephrolithiasis (calculi in the kidneys)
  7. Pain
  8. Renal impairment (severely reduced kidney function)

50-59:

  1. Tendon pain
  2. Upper limb fracture
  3. Arthralgia (joint pain)
  4. Contusion (a type of hematoma of tissue in which capillaries)
  5. Fall
  6. Head injury
  7. Headache (pain in head)
  8. Musculoskeletal discomfort (discomfort in the body's muscles, joints, tendons, ligaments and nerves)
  9. Pain in extremity
  10. Peripheral swelling

60+:

  1. Fatigue (feeling of tiredness)
  2. Drug ineffective
  3. Fall
  4. Memory impairment
  5. Abdominal distension
  6. Arthralgia (joint pain)
  7. Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
  8. Confusional state
  9. Epistaxis (bleed from the nose)
  10. Erythema (redness of the skin)

What are the existing conditions these people have? *

  1. High Blood Cholesterol: 12 people, 14.12%
  2. Pain: 11 people, 12.94%
  3. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 10 people, 11.76%
  4. Diabetes: 10 people, 11.76%
  5. High Blood Pressure: 9 people, 10.59%
  6. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 8 people, 9.41%
  7. Blood Pressure Abnormal: 8 people, 9.41%
  8. Stress And Anxiety: 7 people, 8.24%
  9. Multiple Myeloma (cancer of the plasma cells): 7 people, 8.24%
  10. Type 2 Diabetes: 6 people, 7.06%

* Approximation only. Some reports may have incomplete information.

Do you take Chromium picolinate and Vitamin e?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Chromium picolinate and Vitamin e:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Chromium picolinate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Vitamin e:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Chromium picolinate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Vitamin e and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on chromium and tocopherols and tocotrienols (the active ingredients of Chromium picolinate and Vitamin e, respectively), and Chromium picolinate and Vitamin e (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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