Cialis and Caverject drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cialis (tadalafil) and Caverject (alprostadil). Common drug interactions include drug ineffective among males.

The phase IV clinical study analyzes what interactions people have when they take Cialis and Caverject. It is created by eHealthMe based on reports of 73 people who take the same drugs from the FDA, and is updated regularly.

What is Cialis?

Cialis has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 28,532 Cialis users. Check the latest studies of Cialis.

What is Caverject?

Caverject has active ingredients of alprostadil. It is often used in erection problems. eHealthMe is studying from 2,144 Caverject users. Check the latest studies of Caverject.

On Jul, 16, 2026

73 people who take Cialis and Caverject together, and have interactions are studied.

What are the common drug interactions of Cialis and Caverject, by gender? *:

female:

n/a

male:

Drug ineffective
Erection increased
Penis disorder
Visual acuity reduced (reduced clearness of vision)
Depression
Drug effect decreased
Injection site haematoma (localized swelling filled with blood at injection site)
Anhedonia (inability to experience pleasure from activities usually found enjoyable)
Anorgasmia (type of sexual dysfunction in which a person cannot achieve orgasm, even with adequate stimulation)
Bladder cancer

What are the common drug interactions of Cialis and Caverject, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Device failure

40-49:

Penile pain
Chest pain
Drug hypersensitivity
Erection increased
Surgery
Urinary retention (the inability to completely or partially empty the bladder)
Visual impairment
Drug ineffective
Groin pain
Penis deviation

50-59:

Venous insufficiency (poor circulation of blood caused by damaged or enlarged veins)
Depressed mood
Headache (pain in head)
Hypertension (high blood pressure)
Irritability
Restless legs syndrome (a powerful urge to move your legs)
Abscess (pus)
Back pain
Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
Discomfort

60+:

Drug ineffective
Painful erection
Headache (pain in head)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Nausea (feeling of having an urge to vomit)
Pneumonitis (inflammation of the walls of the alveoli in the lungs)
Pyrexia (fever)
Red blood cell count decreased
Vomiting
Abdominal hernia

What are the existing conditions these people have? *

Depression: 10 people, 13.70%
High Blood Pressure: 9 people, 12.33%
High Blood Cholesterol: 6 people, 8.22%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.22%
Gout (uric acid crystals building up in the body): 4 people, 5.48%
Diabetes: 4 people, 5.48%

* Approximation only. Some reports may have incomplete information.

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