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Cialis and Zoledronic drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cialis (tadalafil) and Zoledronic (zoledronic acid). Common drug interactions include arteriovenous fistula occlusion among males.

The phase IV clinical study analyzes what interactions people have when they take Cialis and Zoledronic. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.

What is Cialis?

Cialis has active ingredients of tadalafil. It is often used in erection problems. eHealthMe is studying from 28,532 Cialis users. Check the latest studies of Cialis.

What is Zoledronic?

Zoledronic has active ingredients of zoledronic acid. eHealthMe is studying from 29,812 Zoledronic users. Check the latest studies of Zoledronic.

On Jul, 13, 2026

40 people who take Cialis and Zoledronic together, and have interactions are studied.

Cialis and Zoledronic drug interactions.

What are the common drug interactions of Cialis and Zoledronic, by gender? *:

female:

n/a

male:

  1. Arteriovenous fistula occlusion
  2. Superinfection
  3. Drug ineffective
  4. Dysgeusia (disorder of the sense of taste)
  5. Food craving
  6. Full blood count decreased
  7. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  8. Hyperhidrosis (abnormally increased sweating)
  9. Influenza like illness
  10. Insomnia (sleeplessness)

What are the common drug interactions of Cialis and Zoledronic, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Anaemia (lack of blood)
  2. Alopecia (absence of hair from areas of the body)
  3. Arteriovenous fistula occlusion
  4. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  5. Dysgeusia (disorder of the sense of taste)
  6. Dyspnoea (difficult or laboured respiration)
  7. Fatigue (feeling of tiredness)
  8. Food craving
  9. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  10. Hyperhidrosis (abnormally increased sweating)

60+:

  1. Superinfection
  2. Arteriovenous fistula occlusion
  3. Arthropathy
  4. Balance disorder
  5. Blood pressure fluctuation
  6. Blood pressure systolic increased
  7. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  8. Constipation
  9. Cough
  10. Deep vein thrombosis (blood clot in a major vein that usually develops in the legs and/or pelvis)

What are the existing conditions these people have? *

  1. Multiple Myeloma (cancer of the plasma cells): 23 people, 57.50%
  2. Raynaud's Phenomenon (discoloration of the fingers, toes, and occasionally other areas): 11 people, 27.50%

* Approximation only. Some reports may have incomplete information.

Do you take Cialis and Zoledronic?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously

Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cialis and Zoledronic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cialis:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Zoledronic:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cialis and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Zoledronic and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on tadalafil and zoledronic acid (the active ingredients of Cialis and Zoledronic, respectively), and Cialis and Zoledronic (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.

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