Cilostazol and Zoloft drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cilostazol (cilostazol) and Zoloft (sertraline hydrochloride). Common drug interactions include bradycardia among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Cilostazol and Zoloft. It is created by eHealthMe based on reports of 69 people who take the same drugs from the FDA, and is updated regularly.
What is Cilostazol?
Cilostazol has active ingredients of cilostazol. It is often used in arteriosclerosis of the extremities. eHealthMe is studying from 7,877 Cilostazol users. Check the latest studies of Cilostazol.
What is Zoloft?
Zoloft has active ingredients of sertraline hydrochloride. It is often used in depression. eHealthMe is studying from 138,798 Zoloft users. Check the latest studies of Zoloft.
69 people who take Cilostazol and Zoloft together, and have interactions are studied.

What are the common drug interactions of Cilostazol and Zoloft, by gender? *:
female:
- Bradycardia (abnormally slow heart action)
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Confusional state
- Decreased appetite
- Dehydration (dryness resulting from the removal of water)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Diarrhoea
- Dizziness
- Drug ineffective
- Dyspepsia (indigestion)
male:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Haemoglobin decreased
- Metastases to bone (cancer spreads to bone)
- Metastases to soft tissue (cancer spreads to soft tissue)
- Nephrogenic anaemia (anaemia due to kidney disease)
- Pain
- Renal injury (kidney injury)
- Somnolence (a state of near-sleep, a strong desire for sleep)
- Atrioventricular block second degree (heart block second degree)
What are the common drug interactions of Cilostazol and Zoloft, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Atrioventricular block second degree (heart block second degree)
- Chest pain
- Chronic kidney disease
- Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
- Hypertension (high blood pressure)
- Lung infection
- Nausea (feeling of having an urge to vomit)
- Nephrolithiasis (calculi in the kidneys)
- Pneumonia
- Pyelonephritis (inflammation of kidney caused by bacteria)
50-59:
- Musculoskeletal stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves)
- Oedema peripheral (superficial swelling)
- Pain
- Quality of life decreased
- Sinusitis (inflammation of sinus)
- Skin tightness
- Tooth extraction
- Bone disorder
- Nasopharyngitis (inflammation of the nasopharynx)
- Skin discolouration (change of skin colour)
60+:
- Chronic kidney disease
- Renal failure (kidney dysfunction)
- Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
- Malaise (a feeling of general discomfort or uneasiness)
- Multiple injuries
- Muscular weakness (muscle weakness)
- Renal injury (kidney injury)
- Urinary tract infection
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 14 people, 20.29%
- High Blood Pressure: 13 people, 18.84%
- High Blood Cholesterol: 12 people, 17.39%
- Pain: 9 people, 13.04%
- Nuclear Magnetic Resonance Imaging Abdominal: 8 people, 11.59%
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 7 people, 10.14%
- Insomnia (sleeplessness): 7 people, 10.14%
- Stress And Anxiety: 6 people, 8.70%
- Infection: 6 people, 8.70%
- Diabetes: 6 people, 8.70%
* Approximation only. Some reports may have incomplete information.
Do you take Cilostazol and Zoloft?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Cilostazol (7,877 reports)
- Zoloft (138,798 reports)
Browse all drug interactions of Cilostazol and Zoloft:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cilostazol:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zoloft:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cilostazol and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zoloft and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
- Izgi C, Erdem G, Mansuroglu D, Kurtoglu N, Kara M, Gunesdogdu F, "Severe hypokalemia probably associated with sertraline use", Annals of Pharmacotherapy, 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cilostazol and sertraline hydrochloride (the active ingredients of Cilostazol and Zoloft, respectively), and Cilostazol and Zoloft (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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