Cimetidine and Creon drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cimetidine (cimetidine) and Creon (pancrelipase (amylase;lipase;protease)). Common drug interactions include hepatic failure among females and abdominal discomfort among males.
The phase IV clinical study analyzes what interactions people have when they take Cimetidine and Creon. It is created by eHealthMe based on reports of 14 people who take the same drugs from the FDA, and is updated regularly.
What is Cimetidine?
Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.
What is Creon?
Creon has active ingredients of pancrelipase (amylase;lipase;protease). It is often used in pancreatitis. eHealthMe is studying from 29,489 Creon users. Check the latest studies of Creon.
14 people who take Cimetidine and Creon together, and have interactions are studied.

What are the common drug interactions of Cimetidine and Creon, by gender? *:
female:
- Hepatic failure (liver failure)
- Chronic kidney disease
- Hepatic cirrhosis (chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue)
- Renal failure (kidney dysfunction)
- Abdominal distension
- Abdominal pain
- Back pain
- Blood glucose increased
- Constipation
- Cystitis (inflammation of the wall of the bladder)
male:
- Abdominal discomfort
- Arthritis (form of joint disorder that involves inflammation of one or more joints)
- Hepatic failure (liver failure)
- Hypertension (high blood pressure)
- Intervertebral disc disorder (spinal disc disorder)
- Myalgia (muscle pain)
- Nerve injury
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Pain
What are the common drug interactions of Cimetidine and Creon, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Constipation
30-39:
- Renal failure (kidney dysfunction)
40-49:
n/a
50-59:
- Dyspepsia (indigestion)
- Fibromyalgia (a long-term condition which causes pain all over the body)
- Gouty arthritis (joint inflammation with crystal formation)
- International normalised ratio increased
- Myalgia (muscle pain)
- Nerve injury
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Pain
- Pharyngeal mass
60+:
- Blood glucose increased
- Cystitis (inflammation of the wall of the bladder)
- Hepatic failure (liver failure)
What are the existing conditions these people have? *
- High Blood Pressure: 7 people, 50.00%
- Multiple Allergies (allergy to multiple agents): 6 people, 42.86%
- Hot Flush (sudden feelings of heat): 5 people, 35.71%
- Joint Pain: 5 people, 35.71%
- Migraine (headache): 4 people, 28.57%
- Pain: 4 people, 28.57%
- Indigestion: 2 people, 14.29%
- Gastric Ph Decreased: 1 person, 7.14%
- Fever: 1 person, 7.14%
- Stress And Anxiety: 1 person, 7.14%
* Approximation only. Some reports may have incomplete information.
Do you take Cimetidine and Creon?
- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously
Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Cimetidine (10,531 reports)
- Creon (29,489 reports)
Browse all drug interactions of Cimetidine and Creon:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cimetidine:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Creon:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cimetidine and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Creon and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zHow the study uses the data?
The study uses data from the FDA. It is based on cimetidine and pancrelipase (amylase;lipase;protease) (the active ingredients of Cimetidine and Creon, respectively), and Cimetidine and Creon (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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