Cimetidine and Lamisil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cimetidine (cimetidine) and Lamisil (terbinafine hydrochloride). Common drug interactions include gastrointestinal haemorrhage among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Cimetidine and Lamisil. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Cimetidine?

Cimetidine has active ingredients of cimetidine. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 10,531 Cimetidine users. Check the latest studies of Cimetidine.

What is Lamisil?

Lamisil has active ingredients of terbinafine hydrochloride. It is often used in pulmonary aspergilloma (mycetoma). eHealthMe is studying from 14,080 Lamisil users. Check the latest studies of Lamisil.



On Jul, 19, 2026

22 people who take Cimetidine and Lamisil together, and have interactions are studied.

Cimetidine and Lamisil drug interactions.

What are the common drug interactions of Cimetidine and Lamisil, by gender? *:

female:

  1. Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
  2. International normalised ratio increased
  3. Melaena (the passage of black, tarry stools)
  4. Osteoporosis (bones weak and more likely to break)
  5. Renal failure (kidney dysfunction)
  6. Renal failure chronic (long lasting kidney dysfunction)
  7. Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
  8. Skin ulcer
  9. Anaemia (lack of blood)
  10. Asthenia (weakness)

male:

  1. Chronic kidney disease
  2. Depression
  3. Liver disorder (liver diseases)
  4. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)
  5. Renal cyst (kidney cyst)
  6. Renal failure (kidney dysfunction)
  7. Renal tubular necrosis (death of kidney tubules)

What are the common drug interactions of Cimetidine and Lamisil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Chronic kidney disease
  2. Hyperkalaemia (damage to or disease of the kidney)
  3. Hyperparathyroidism secondary (an abnormally high concentration of parathyroid hormone in the blood, resulting in weakening of the bones through loss of calcium-secondary)
  4. Nephrogenic anaemia (anaemia due to kidney disease)
  5. Renal failure (kidney dysfunction)
  6. Renal hypertension (high blood pressure caused by the kidneys hormonal response)

40-49:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Renal tubular necrosis (death of kidney tubules)
  4. Tubulointerstitial nephritis (a form of nephritis affecting the interstitium of the kidneys surrounding the tubules)

50-59:

  1. Nephritis interstitial (a kidney condition characterized by swelling in between the kidney tubules)
  2. Renal impairment (severely reduced kidney function)
  3. Renal failure chronic (long lasting kidney dysfunction)
  4. Sjogren's syndrome (a disease that causes dryness in the mouth and eyes)
  5. Blood potassium increased
  6. White blood cell count increased

60+:

  1. Chronic kidney disease
  2. Depression
  3. Chromosome abnormality (abnormal gene structure pattern)
  4. Granulocytopenia (lack of granulocyte)
  5. Haematocrit decreased
  6. Haemoglobin decreased
  7. Pneumonia
  8. Prothrombin level decreased
  9. Renal cyst (kidney cyst)
  10. Renal failure (kidney dysfunction)

What are the existing conditions these people have? *

  1. Diabetes: 7 people, 31.82%
  2. Thrombosis (formation of a blood clot inside a blood vessel): 6 people, 27.27%
  3. Gastrointestinal Disorder (functional problems of gastrointestinal tract): 6 people, 27.27%
  4. Dyspnea (difficult or laboured breathing): 6 people, 27.27%
  5. Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 2 people, 9.09%
  6. Infection: 2 people, 9.09%
  7. High Blood Cholesterol: 2 people, 9.09%
  8. Depression: 2 people, 9.09%
  9. Athlete's Foot (a fungal infection affecting the skin between the toes): 2 people, 9.09%

* Approximation only. Some reports may have incomplete information.

Do you take Cimetidine and Lamisil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Cimetidine and Lamisil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Cimetidine:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Lamisil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Cimetidine and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Lamisil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on cimetidine and terbinafine hydrochloride (the active ingredients of Cimetidine and Lamisil, respectively), and Cimetidine and Lamisil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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