Cipro and Actigall drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cipro (ciprofloxacin hydrochloride) and Actigall (ursodiol). Common drug interactions include clostridial infection among females and anaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Cipro and Actigall. It is created by eHealthMe based on reports of 64 people who take the same drugs from the FDA, and is updated regularly.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

What is Actigall?

Actigall has active ingredients of ursodiol. It is often used in gallstones. eHealthMe is studying from 2,162 Actigall users. Check the latest studies of Actigall.

On Jul, 19, 2026

64 people who take Cipro and Actigall together, and have interactions are studied.

What are the common drug interactions of Cipro and Actigall, by gender? *:

female:

Clostridial infection (infectious conditions by clostridium bacteria)
Coagulopathy (blood's ability to clot is impaired)
Cytomegalovirus antigen positive
Decreased appetite
Diarrhoea
Disease progression
Drug ineffective
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)

male:

Anaemia (lack of blood)
Pyrexia (fever)
Acute respiratory distress syndrome
Asthenia (weakness)
Bandaemia (excess of band cells (immature white blood cells) released by the bone marrow into the blood)
Blood creatinine increased
Blood urea increased
Bronchial haemorrhage (bleeding in bronchia)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Constipation

What are the common drug interactions of Cipro and Actigall, by age (0-1 to 60+)? *:

0-1:

Abdominal distension
Ascites (accumulation of fluid in the abdominal cavity)
Eyelid oedema (eyelids are swollen and contain excessive fluid)
Peritonitis bacterial (inflammation of the peritoneum, the thin tissue that lines the inner wall of the abdomen and covers most of the abdominal organs by bacterial)
Pyrexia (fever)

2-9:

n/a

10-19:

Blood amylase increased
Cough
Ependymoma malignant (cancer in the brain)
Febrile convulsion (a convulsion associated with a significant rise in body temperature)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Lower respiratory tract infection viral
Oesophagitis (inflammation of oesophagus)
Secondary immunodeficiency (lack of immunity due to some disease)
Sepsis (a severe blood infection that can lead to organ failure and death)

20-29:

Rash
Anaphylactic reaction (serious allergic reaction)
Blood lactate dehydrogenase increased
Cytomegalovirus antigen positive
Diarrhoea
Disease progression
Graft versus host disease (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body)
Hypoglycaemia (deficiency of glucose in the bloodstream)
Hypomagnesaemia (electrolyte disturbance in which there is an abnormally low level of magnesium in the blood)
Mucosal inflammation (infection of mucous membrane)

30-39:

Bronchial haemorrhage (bleeding in bronchia)
Bronchitis chronic (inflammation of the mucous membrane in the bronchial tubes- chronic)
Constipation
Cough
Cystic fibrosis (disease of the secretary glands)
Diarrhoea
Dysphagia (a condition in which swallowing is difficult or painful)
Dyspnoea (difficult or laboured respiration)
Gastroenteritis norovirus (inflammation of stomach and intestine caused by norovirus infection)
Gastrointestinal disorder (functional problems of gastrointestinal tract)

40-49:

Anaemia (lack of blood)
Bile duct stricture (narrowed areas of the bile ducts that can be either benign or malignant)
Blood amylase increased
Blood bilirubin increased
Cholangitis (infection of the bile duct)
Lethargy (tiredness)
Pancreatitis (inflammation of pancreas)
Pyrexia (fever)

50-59:

Bacteraemia (presence of bacteria in the blood)
Fatigue (feeling of tiredness)
Fluid overload (too much fluid in the blood)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Vomiting
Abdominal pain
Blood iron increased
Confusion
Crohn's disease (a condition that causes inflammation of the gastrointestinal tract)
Dehydration (dryness resulting from the removal of water)

60+:

Abdominal pain
Ascites (accumulation of fluid in the abdominal cavity)
Multi-organ failure (multisystem organ failure)
Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
Post procedural haemorrhage (post procedural bleeding)
Renal failure acute (rapid kidney dysfunction)
Staphylococcal infection (an infection with staphylococcus bacteria)
Blood bilirubin increased
Abdominal distension
Abdominal pain upper

What are the existing conditions these people have? *

Pain: 19 people, 29.69%
Nausea (feeling of having an urge to vomit): 16 people, 25.00%
Cystic Fibrosis (disease of the secretary glands): 14 people, 21.88%
Cough: 13 people, 20.31%
High Blood Pressure: 12 people, 18.75%
Bronchitis (inflammation of the mucous membrane in the bronchial tubes): 12 people, 18.75%
Fungal Infection: 12 people, 18.75%
Inflammation: 11 people, 17.19%
Wheezing (a high-pitched whistling sound made while you breath): 11 people, 17.19%
Sedation: 11 people, 17.19%

* Approximation only. Some reports may have incomplete information.

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