Cipro and Dipyrone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cipro (ciprofloxacin hydrochloride) and Dipyrone (metamizole). Common drug interactions include visual acuity reduced among females and acute hepatic failure among males.

The phase IV clinical study analyzes what interactions people have when they take Cipro and Dipyrone. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

What is Dipyrone?

Dipyrone has active ingredients of metamizole. eHealthMe is studying from 1,876 Dipyrone users. Check the latest studies of Dipyrone.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Sep, 02, 2026

13 people who take Cipro and Dipyrone together, and have interactions are studied.

What are the common drug interactions of Cipro and Dipyrone, by gender? *:

female:

Visual acuity reduced (reduced clearness of vision)
Weight increased
Diarrhoea
Weight decreased
Abdominal pain
Back pain
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Butterfly rash
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chest pain

male:

Acute hepatic failure
Agitation (state of anxiety or nervous excitement)
Coma (state of unconsciousness lasting more than six hours)
Depressed level of consciousness
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Irritability
Respiratory failure (inadequate gas exchange by the respiratory system)
Multi-organ failure (multisystem organ failure)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Acute abdomen

What are the common drug interactions of Cipro and Dipyrone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Hypotension (abnormally low blood pressure)
Immunosuppressant drug level decreased
Neurological decompensation (inability of brain to maintain proper function)
Nystagmus (a condition of involuntary eye movement)
Partial seizures (seizures which affect only a part of the brain at onset)
Respiratory disorder (respiratory disease)
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)
Vasculitis (inflammation of a blood vessel or blood vessels)
Visual acuity reduced (reduced clearness of vision)

10-19:

n/a

20-29:

Respiratory failure (inadequate gas exchange by the respiratory system)
Abdominal pain
Agitation (state of anxiety or nervous excitement)
Anxiety
Back pain
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Butterfly rash
Cardio-respiratory arrest (sudden dysfunction of heart and lungs)
Chest pain
Coma (state of unconsciousness lasting more than six hours)

30-39:

n/a

40-49:

n/a

50-59:

Conjunctivitis (pink eye)
Dermatitis exfoliative (widespread scaling of the skin, often with itching (pruritus), skin redness (erythroderma), and hair loss)
Oral mucosal blistering (mouth ulcer)
Pain
Pruritus (severe itching of the skin)
Pyrexia (fever)
Stevens johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)

60+:

Acute hepatic failure
Cardiac failure acute
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Drug administration error
Fall
General physical condition
Leukopenia (less number of white blood cells in blood)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Overdose

What are the existing conditions these people have? *

Extravasation (leakage of a fluid): 2 people, 15.38%
Breast Cancer: 1 person, 7.69%
Abdominal Infection: 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

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