Cipro and Levophed drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cipro (ciprofloxacin hydrochloride) and Levophed (norepinephrine bitartrate). Common drug interactions include pancytopenia among females and sepsis among males.

The phase IV clinical study analyzes what interactions people have when they take Cipro and Levophed. It is created by eHealthMe based on reports of 70 people who take the same drugs from the FDA, and is updated regularly.

What is Cipro?

Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.

What is Levophed?

Levophed has active ingredients of norepinephrine bitartrate. eHealthMe is studying from 2,047 Levophed users. Check the latest studies of Levophed.

On Jul, 06, 2026

70 people who take Cipro and Levophed together, and have interactions are studied.

What are the common drug interactions of Cipro and Levophed, by gender? *:

female:

Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Confusional state
Platelet count decreased
Respiratory distress (difficulty in breathing)
Staphylococcal infection (an infection with staphylococcus bacteria)
Thrombocytopenia (decrease of platelets in blood)
Cardiac arrest
Nausea (feeling of having an urge to vomit)
Pain
Pulmonary fibrosis (formation or development of excess fibrous connective tissue (fibrosis) in the lungs)

male:

Sepsis (a severe blood infection that can lead to organ failure and death)
Injury
Haemoglobin decreased
Hypotension (abnormally low blood pressure)
Hypoxia (low oxygen in tissues)
Multi-organ failure (multisystem organ failure)
Nervousness
Pleural effusion (water on the lungs)
Pneumonia
Renal injury (kidney injury)

What are the common drug interactions of Cipro and Levophed, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

Respiratory disorder (respiratory disease)
Pulmonary vascular disorder

30-39:

Caecitis (inflammation of the cecum)
Colitis ischaemic (due to infection of intestine impaired blood supply to colon)
Hypersensitivity
Sepsis (a severe blood infection that can lead to organ failure and death)

40-49:

Hyperpyrexia (extremely high fever)
Ileus (a painful obstruction of the ileum or other part of the intestine)
Pneumonia
Sepsis (a severe blood infection that can lead to organ failure and death)
Septic shock (shock due to blood infection)
Anxiety
Body temperature increased
Cardiac arrest
Cardiopulmonary failure (cessation of normal circulation of the blood due to failure of the heart to contract)
Depression

50-59:

Activated partial thromboplastin time prolonged
Acute respiratory failure
Atrioventricular block first degree (heart block first degree)
Bacteria urine identified
Blood calcium decreased
Blood urea increased
Conjunctival haemorrhage (bleeding underneath the conjunctiva)
Gastrointestinal haemorrhage (bleeding gastrointestinal tract)
Gastrointestinal necrosis (destruction of gastrointestinal organ)
Haematocrit decreased

60+:

Sepsis (a severe blood infection that can lead to organ failure and death)
Respiratory failure (inadequate gas exchange by the respiratory system)
Septic shock (shock due to blood infection)
Leukocytosis (increased white blood cells)
Confusional state
Platelet count decreased
Staphylococcal infection (an infection with staphylococcus bacteria)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Thrombocytopenia (decrease of platelets in blood)
Decreased appetite

What are the existing conditions these people have? *

Pain: 16 people, 22.86%
Nausea (feeling of having an urge to vomit): 14 people, 20.00%
Nausea And Vomiting: 8 people, 11.43%
Hypotension (abnormally low blood pressure): 7 people, 10.00%
High Blood Pressure: 7 people, 10.00%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 7 people, 10.00%
Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 6 people, 8.57%
Pneumonia: 6 people, 8.57%
Sepsis (a severe blood infection that can lead to organ failure and death): 6 people, 8.57%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 8.57%

* Approximation only. Some reports may have incomplete information.

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