Cipro and Ticlid drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cipro (ciprofloxacin hydrochloride) and Ticlid (ticlopidine hydrochloride). Common drug interactions include hypokalaemia among females and chronic kidney disease among males.
The phase IV clinical study analyzes what interactions people have when they take Cipro and Ticlid. It is created by eHealthMe based on reports of 28 people who take the same drugs from the FDA, and is updated regularly.
What is Cipro?
Cipro has active ingredients of ciprofloxacin hydrochloride. It is often used in urinary tract infection. eHealthMe is studying from 35,126 Cipro users. Check the latest studies of Cipro.
What is Ticlid?
Ticlid has active ingredients of ticlopidine hydrochloride. eHealthMe is studying from 3,094 Ticlid users. Check the latest studies of Ticlid.
28 people who take Cipro and Ticlid together, and have interactions are studied.

What are the common drug interactions of Cipro and Ticlid, by gender? *:
female:
- Hypokalaemia (low potassium)
- Hyponatraemia (abnormally low level of sodium in the blood; associated with dehydration)
- Lethargy (tiredness)
- Malnutrition (a condition that results from eating a diet in which certain nutrients are lacking)
- Myocardial infarction (destruction of heart tissue resulting from obstruction of the blood supply to the heart muscle)
- Oral disorder (mouth disease)
- Osteoarthritis (a joint disease caused by cartilage loss in a joint)
- Overdose
- Proteinuria (presence of protein in the urine)
- Pyrexia (fever)
male:
- Chronic kidney disease
- Pneumonia
- Cardiogenic shock (inadequate circulation of blood)
- Cardiomegaly (increased size of heart than normal)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Cough
- Diabetes mellitus inadequate control
- Emotional distress
- Hyperhidrosis (abnormally increased sweating)
- Hypokalaemia (low potassium)
What are the common drug interactions of Cipro and Ticlid, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Headache (pain in head)
- Weakness
- Nausea (feeling of having an urge to vomit)
- Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
- Dysarthria (speech disorder)
- Lethargy (tiredness)
- Pyrexia (fever)
- Salivary hypersecretion (excess saliva secretion)
- Shivering
- Vomiting
50-59:
- Thrombotic thrombocytopenic purpura (a rare blood disorder characterized by clotting in small blood vessels of the body)
60+:
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Hypokalaemia (low potassium)
- Diabetes mellitus inadequate control
- Emotional distress
- Hyperhidrosis (abnormally increased sweating)
- Mental disorder (a psychological term for a mental or behavioural pattern or anomaly that causes distress or disability)
- Occult blood positive
- Pain
- Palpitations (feelings or sensations that your heart is pounding or racing)
- Pneumonia
What are the existing conditions these people have? *
- Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 6 people, 21.43%
- Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 6 people, 21.43%
- Pain: 6 people, 21.43%
- High Blood Pressure: 6 people, 21.43%
- High Blood Cholesterol: 4 people, 14.29%
- Arthritis (form of joint disorder that involves inflammation of one or more joints): 4 people, 14.29%
- Asthma: 4 people, 14.29%
- Bacterial Infection: 4 people, 14.29%
- Thrombosis (formation of a blood clot inside a blood vessel): 4 people, 14.29%
- Malaria (a parasitic disease due to mosquito bite): 4 people, 14.29%
* Approximation only. Some reports may have incomplete information.
Do you take Cipro and Ticlid?
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Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cipro and Ticlid:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cipro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Ticlid:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cipro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Ticlid and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
- Jacob S, Dunn BL, Qureshi ZP, Bandarenko N, Kwaan HC, Pandey DK, McKoy JM, Barnato SE, Winters JL, Cursio JF, Weiss I, "Ticlopidine-, clopidogrel-, and prasugrel-associated thrombotic thrombocytopenic purpura: a 20-year review from the Southern Network on Adverse Reactions (SONAR)", InSeminars in thrombosis and hemostasis, 2012 Jan .
- Frank P, "Ticlopidine-, Clopidogrel-, and Prasugrel-Associated Thrombotic Thrombocytopenic Purpura: A Twenty-Year Review from the Southern Network on Adverse Reactions (SONAR)", , 2012 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on ciprofloxacin hydrochloride and ticlopidine hydrochloride (the active ingredients of Cipro and Ticlid, respectively), and Cipro and Ticlid (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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