Cisplatin and Fentanyl-100 drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Cisplatin (cisplatin) and Fentanyl-100 (fentanyl). Common drug interactions include vomiting among females and hypotension among males.

The phase IV clinical study analyzes what interactions people have when they take Cisplatin and Fentanyl-100. It is created by eHealthMe based on reports of 45 people who take the same drugs from the FDA, and is updated regularly.

What is Cisplatin?

Cisplatin has active ingredients of cisplatin. It is often used in chemotherapy. eHealthMe is studying from 92,837 Cisplatin users. Check the latest studies of Cisplatin.

What is Fentanyl-100?

Fentanyl-100 has active ingredients of fentanyl. It is often used in pain. eHealthMe is studying from 7,047 Fentanyl-100 users. Check the latest studies of Fentanyl-100.

eHealthMe: drug outcomes in the real world

eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.

On Jul, 02, 2026

45 people who take Cisplatin and Fentanyl-100 together, and have interactions are studied.

Cisplatin and Fentanyl-100 drug interactions.

What are the common drug interactions of Cisplatin and Fentanyl-100, by gender? *:

female:

Vomiting
Nausea (feeling of having an urge to vomit)
Anxiety
Pyrexia (fever)
Herpes zoster
Productive cough
Stomatitis (inflammation of mucous membrane of mouth)
Mucosal inflammation (infection of mucous membrane)
Alanine aminotransferase increased
Aspartate aminotransferase increased

male:

Hypotension (abnormally low blood pressure)
Anaemia (lack of blood)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Hepatic enzyme increased
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Therapeutic response decreased (less preventive response)
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Cholangitis (infection of the bile duct)
Drug effect decreased

What are the common drug interactions of Cisplatin and Fentanyl-100, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Anxiety
Depression
Injury
Post-traumatic stress disorder
Pulmonary embolism (blockage of the main artery of the lung)

20-29:

n/a

30-39:

Neoplasm progression (growth of tumour)
Anaemia (lack of blood)
Bile duct obstruction (blockage in the tubes that carry bile from the liver to the gallbladder)
Cholangitis (infection of the bile duct)
Confusional state
Drug effect decreased
Dysphagia (a condition in which swallowing is difficult or painful)
General physical health deterioration (weak health status)
Hallucination (an experience involving the perception of something not present)
Hypotension (abnormally low blood pressure)

40-49:

Anaemia (lack of blood)
Weight decreased
Coma (state of unconsciousness lasting more than six hours)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Disorientation (disability in which the senses of time, direction, and recognition of people and places)
Hallucination (an experience involving the perception of something not present)
Hepatic enzyme increased
Hypotension (abnormally low blood pressure)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Neoplasm progression (growth of tumour)

50-59:

Multiple myeloma (cancer of the plasma cells)
Renal failure acute (rapid kidney dysfunction)
Thrombocytopenia (decrease of platelets in blood)
Tumour lysis syndrome (a group of metabolic complications that can occur after treatment of cancer, these complications are caused by the breakdown products of dying cancer cells)
Haematemesis (vomiting of blood)
Hypercalcaemia (elevated calcium (ca+) level in the blood)
Interstitial lung disease
Mucosal inflammation (infection of mucous membrane)
Respiratory failure (inadequate gas exchange by the respiratory system)
Reversible posterior leukoencephalopathy syndrome (a brain disease with generalized seizures and headache)

60+:

Anaemia (lack of blood)
Dehydration (dryness resulting from the removal of water)
Decreased appetite
Drug ineffective
Hypoxia (low oxygen in tissues)
Nausea (feeling of having an urge to vomit)
Vomiting
Agitation (state of anxiety or nervous excitement)
Alanine aminotransferase increased
Anxiety

What are the existing conditions these people have? *

Oral Cancer (mouth cancer): 12 people, 26.67%
Nausea (feeling of having an urge to vomit): 11 people, 24.44%
Cancer Pain: 7 people, 15.56%
Stress And Anxiety: 6 people, 13.33%
Lung Cancer - Non-Small Cell (lung cancer): 4 people, 8.89%
Thrombosis (formation of a blood clot inside a blood vessel): 3 people, 6.67%
Oropharyngeal Pain: 3 people, 6.67%
High Blood Cholesterol: 3 people, 6.67%
Diabetes: 3 people, 6.67%
Constipation: 3 people, 6.67%

* Approximation only. Some reports may have incomplete information.

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