Cisplatin and Versed drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cisplatin (cisplatin) and Versed (midazolam hydrochloride). Common drug interactions include injury among females and dyspnoea among males.
The phase IV clinical study analyzes what interactions people have when they take Cisplatin and Versed. It is created by eHealthMe based on reports of 40 people who take the same drugs from the FDA, and is updated regularly.
What is Cisplatin?
Cisplatin has active ingredients of cisplatin. It is often used in chemotherapy. eHealthMe is studying from 92,837 Cisplatin users. Check the latest studies of Cisplatin.
What is Versed?
Versed has active ingredients of midazolam hydrochloride. It is often used in sedation during medical procedure. eHealthMe is studying from 6,869 Versed users. Check the latest studies of Versed.
40 people who take Cisplatin and Versed together, and have interactions are studied.

What are the common drug interactions of Cisplatin and Versed, by gender? *:
female:
- Injury
- Bone disorder
- Erythema (redness of the skin)
- Swelling
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Depression
- Disability
- Oral disorder (mouth disease)
- Abdominal pain
- Amnesia (deficit in memory caused by brain damage, disease, or psychological trauma)
male:
- Dyspnoea (difficult or laboured respiration)
- Pyrexia (fever)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Hypertension (high blood pressure)
- Lethargy (tiredness)
- Multi-organ failure (multisystem organ failure)
- Refractory cancer (cancer that has not responded to treatment)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Anxiety
- Injury
What are the common drug interactions of Cisplatin and Versed, by age (0-1 to 60+)? *:
0-1:
- Abdominal distension
- Alopecia (absence of hair from areas of the body)
- Blister (small pocket of fluid within the upper layers of the skin caused by forceful rubbing (friction), burning, freezing, chemical exposure)
- Candidiasis (candidiasis or thrush is a fungal infection)
- Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
- Failure to thrive (inadequate weight gain and physical growth in children)
- Fluid overload (too much fluid in the blood)
- Gastroenteritis (inflammation of stomach and intestine)
- Hypertension (high blood pressure)
- Hypotension (abnormally low blood pressure)
2-9:
n/a
10-19:
- Anxiety
- Depression
- Injury
- Pain
- Post-traumatic stress disorder
- Pulmonary embolism (blockage of the main artery of the lung)
20-29:
n/a
30-39:
n/a
40-49:
- Anxiety
- Anaemia (lack of blood)
- Bronchial metaplasia (abnormal change in the nature of a tissue in bronchia)
- Cardiogenic shock (inadequate circulation of blood)
- Cough
- Death
- Depression
- Device dislocation
- Dry skin
- Dyspnoea (difficult or laboured respiration)
50-59:
- Pain
- Acute pulmonary oedema (sudden deposit of fluid in the lung))
- Death
- Lobar pneumonia (a form of pneumonia that affects a large and continuous area of the lobe of a lung)
- Oral soft tissue disorder (oral soft tissue disease)
- Abscess (pus)
- Bronchial carcinoma (lung cancer)
- Bone disorder
- Erythema (redness of the skin)
- Swelling
60+:
- Supraventricular tachycardia (rapid heart rhythm originating at or above the atrioventricular node)
- Cardiac arrest
- Disturbance in attention
- Lethargy (tiredness)
- Muscular weakness (muscle weakness)
- Pain
- Pulmonary embolism (blockage of the main artery of the lung)
- Respiratory failure (inadequate gas exchange by the respiratory system)
What are the existing conditions these people have? *
- Lung Cancer - Non-Small Cell (lung cancer): 18 people, 45.00%
- Hypercalcaemia Of Malignancy (elevated calcium (ca+) level in the blood with cancer): 17 people, 42.50%
- Pain: 8 people, 20.00%
- Nausea (feeling of having an urge to vomit): 7 people, 17.50%
- Constipation: 6 people, 15.00%
- Multiple Myeloma (cancer of the plasma cells): 5 people, 12.50%
- Hyperlipidaemia (presence of excess lipids in the blood): 4 people, 10.00%
- High Blood Pressure: 4 people, 10.00%
- Blood Glucose Fluctuation: 4 people, 10.00%
- Nausea And Vomiting: 3 people, 7.50%
* Approximation only. Some reports may have incomplete information.
Do you take Cisplatin and Versed?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cisplatin and Versed:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cisplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Versed:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cisplatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Versed and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cisplatin and midazolam hydrochloride (the active ingredients of Cisplatin and Versed, respectively), and Cisplatin and Versed (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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