Cisplatin and Zerit drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Cisplatin (cisplatin) and Zerit (stavudine). Common drug interactions include cervix carcinoma among females and angina pectoris among males.
The phase IV clinical study analyzes what interactions people have when they take Cisplatin and Zerit. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.
What is Cisplatin?
Cisplatin has active ingredients of cisplatin. It is often used in chemotherapy. eHealthMe is studying from 92,837 Cisplatin users. Check the latest studies of Cisplatin.
What is Zerit?
Zerit has active ingredients of stavudine. eHealthMe is studying from 9,912 Zerit users. Check the latest studies of Zerit.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
19 people who take Cisplatin and Zerit together, and have interactions are studied.

What are the common drug interactions of Cisplatin and Zerit, by gender? *:
female:
- Cervix carcinoma (cancer of cervix)
- General physical health deterioration (weak health status)
- Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
- Renal impairment (severely reduced kidney function)
- Ventricular tachycardia (rapid heartbeat that originates in one of the lower chambers (the ventricles) of the heart)
male:
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Dehydration (dryness resulting from the removal of water)
- Diarrhoea
- Dizziness
- Emotional distress
- Hyperlipidaemia (presence of excess lipids in the blood)
- Hypokinesia (decreased bodily movement)
- Infusion related reaction
- Lipodystrophy acquired (a regional loss of subcutaneous adipose tissue which usually starts in the face, extends downward acquired)
What are the common drug interactions of Cisplatin and Zerit, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Angina pectoris (chest pain due to ischemia of the heart muscle)
- Coronary artery disease (plaque building up along the inner walls of the arteries of the heart, which narrows the arteries and restricts blood flow to the heart)
- Non-hodgkin's lymphoma (malignant (cancer) cells form in the lymph system)
- Bone density decreased
- Bone loss
- Emotional distress
- Hypokinesia (decreased bodily movement)
- Lung neoplasm (tumour of lung)
- Neutropenia (an abnormally low number of neutrophils)
- Osteonecrosis (death of bone)
50-59:
- Acute prerenal failure (prerenal acute renal failure (arf) occurs when a sudden reduction in blood flow to the kidney)
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
- Dehydration (dryness resulting from the removal of water)
- Nausea (feeling of having an urge to vomit)
- Vomiting
60+:
n/a
What are the existing conditions these people have? *
- Hiv Infection: 15 people, 78.95%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 7 people, 36.84%
- Hyperuricaemia (level of uric acid in the blood that is abnormally high): 7 people, 36.84%
- Hyperlipidaemia (presence of excess lipids in the blood): 7 people, 36.84%
- Gastric Ulcer (stomach ulcer): 7 people, 36.84%
- Cervix Carcinoma (cancer of cervix): 7 people, 36.84%
- Non-Hodgkin's Lymphoma (malignant (cancer) cells form in the lymph system): 3 people, 15.79%
- Neoplasm Malignant (cancer tumour): 1 person, 5.26%
- Birth Control: 1 person, 5.26%
* Approximation only. Some reports may have incomplete information.
Do you take Cisplatin and Zerit?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Cisplatin and Zerit:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Cisplatin:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zerit:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Cisplatin and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zerit and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
- Schlumbrecht MP, Hehr K, "Cisplatin-induced bradycardia and the importance of the QT interval", Journal of Oncology Pharmacy Practice, 2015 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on cisplatin and stavudine (the active ingredients of Cisplatin and Zerit, respectively), and Cisplatin and Zerit (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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