Citalopram hydrobromide and Tracleer drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Citalopram hydrobromide (citalopram hydrobromide) and Tracleer (bosentan). Common drug interactions include respiratory distress among females and cerebral ischaemia among males.

The phase IV clinical study analyzes what interactions people have when they take Citalopram hydrobromide and Tracleer. It is created by eHealthMe based on reports of 63 people who take the same drugs from the FDA, and is updated regularly.

What is Citalopram hydrobromide?

Citalopram hydrobromide has active ingredients of citalopram hydrobromide. It is often used in depression. eHealthMe is studying from 36,878 Citalopram hydrobromide users. Check the latest studies of Citalopram hydrobromide.

What is Tracleer?

Tracleer has active ingredients of bosentan. It is often used in primary pulmonary hypertension. eHealthMe is studying from 55,125 Tracleer users. Check the latest studies of Tracleer.



On Jul, 06, 2026

63 people who take Citalopram hydrobromide and Tracleer together, and have interactions are studied.

Citalopram hydrobromide and Tracleer drug interactions.

What are the common drug interactions of Citalopram Hydrobromide and Tracleer, by gender? *:

female:

  1. Respiratory distress (difficulty in breathing)
  2. Urinary tract infection
  3. Abdominal pain upper
  4. Agitation (state of anxiety or nervous excitement)
  5. Anaemia (lack of blood)
  6. Anaphylactic reaction (serious allergic reaction)
  7. Angina pectoris (chest pain due to ischemia of the heart muscle)
  8. Blood glucose fluctuation
  9. Blood lactate dehydrogenase increased
  10. Blood pressure diastolic decreased

male:

  1. Cerebral ischaemia (insufficient blood flow to the brain to meet metabolic demand)
  2. Gait disturbance
  3. Vasculitis (inflammation of a blood vessel or blood vessels)
  4. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  5. Atrioventricular block complete (heart block complete)
  6. Cardiac arrest
  7. Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
  8. Disease progression
  9. Dyspnoea (difficult or laboured respiration)
  10. Headache (pain in head)

What are the common drug interactions of Citalopram Hydrobromide and Tracleer, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Anaphylactic reaction (serious allergic reaction)
  2. Angina pectoris (chest pain due to ischemia of the heart muscle)
  3. Blood glucose fluctuation
  4. Blood pressure diastolic decreased
  5. Diabetes mellitus inadequate control
  6. Dizziness
  7. Fall
  8. Head injury
  9. Hydronephrosis (water inside the kidney)
  10. Hypoaesthesia (reduced sense of touch or sensation)

30-39:

  1. Dyspnoea (difficult or laboured respiration)
  2. Angioedema (rapid swelling of the dermis)
  3. Deformity (disfigurement)
  4. Meningitis (inflammation of the protective membranes covering the brain and spinal cord, known collectively as the meninges)
  5. Tenderness (pain or discomfort when an affected area is touched)
  6. Toxic shock syndrome (a rare but serious medical condition caused by a bacterial infection)
  7. Urticaria (rash of round, red welts on the skin that itch intensely)
  8. Chest discomfort
  9. Colostomy
  10. Cough

40-49:

  1. Embolism (obstruction of an artery, typically by a clot of blood or an air bubble)
  2. Pneumonia
  3. Pseudomonal sepsis (pseudomonas infections are diseases caused by a bacterium from the genus pseudomonas)
  4. Pseudomonas infection (pseudomonas infection is caused by a bacterium, pseudomonas aeruginosa)
  5. Coccidioidomycosis (serious disease of the lungs and other tissues, caused by the fungus coccidioides immitis)
  6. Hepatomegaly (abnormal enlargement of the liver)
  7. Pancreatitis (inflammation of pancreas)
  8. Pneumonia pseudomonal (pseudomonas pneumonia is an infection caused by the microbe known as pseudomonas aeruginosa)
  9. Sepsis (a severe blood infection that can lead to organ failure and death)

50-59:

  1. Pleural fibrosis (formation of fibrous tissue in lung)
  2. Eosinophilic pneumonia (eosinophil accumulates in the lung)
  3. Haemolysis (breaking open of red blood cells and the release of haemoglobin into the surrounding fluid)
  4. Haemorrhage (bleeding)
  5. Renal failure (kidney dysfunction)
  6. Hospitalisation
  7. Anaemia (lack of blood)
  8. Blood bilirubin increased
  9. Blood lactate dehydrogenase increased
  10. Decreased appetite

60+:

  1. Alanine aminotransferase increased
  2. Aspartate aminotransferase increased
  3. Cachexia (loss of weight)
  4. Pulmonary hypertension (increase in blood pressure in the lung artery)
  5. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  6. Cardiac failure congestive
  7. Flushing (the warm, red condition of human skin)
  8. Gastrooesophageal reflux disease (stomach contents (food or liquid) leak backwards from the stomach into the oesophagus)
  9. Influenza
  10. Palpitations (feelings or sensations that your heart is pounding or racing)

What are the existing conditions these people have? *

  1. Pulmonary Hypertension (increase in blood pressure in the lung artery): 22 people, 34.92%
  2. Oedema Peripheral (superficial swelling): 5 people, 7.94%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Citalopram hydrobromide and Tracleer:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Citalopram hydrobromide:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Tracleer:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Citalopram hydrobromide and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Tracleer and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on citalopram hydrobromide and bosentan (the active ingredients of Citalopram hydrobromide and Tracleer, respectively), and Citalopram hydrobromide and Tracleer (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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