Citicoline and Aspirin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Citicoline (citicoline) and Aspirin (aspirin). Common drug interactions include cerebrovascular accident among females and fatigue among males.

The phase IV clinical study analyzes what interactions people have when they take Citicoline and Aspirin. It is created by eHealthMe based on reports of 75 people who take the same drugs from the FDA, and is updated regularly.

What is Citicoline?

Citicoline has active ingredients of citicoline. eHealthMe is studying from 508 Citicoline users. Check the latest studies of Citicoline.

What is Aspirin?

Aspirin has active ingredients of aspirin. It is often used in blood clots. eHealthMe is studying from 632,088 Aspirin users. Check the latest studies of Aspirin.



On Jul, 16, 2026

75 people who take Citicoline and Aspirin together, and have interactions are studied.

Citicoline and Aspirin drug interactions.

What are the common drug interactions of Citicoline and Aspirin, by gender? *:

female:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Circulatory collapse
  3. Coma (state of unconsciousness lasting more than six hours)
  4. Compression fracture (fracture due to pressure caused by injury)
  5. Cutaneous leishmaniasis (infection by leishmaniasis produces ulcers on the exposed parts of the body, such as the face, arms and legs)
  6. Cyanosis (lack of oxygen in body leads to blue appearance of skin ,mucous membrane nails)
  7. Discomfort
  8. Disease recurrence
  9. Dizziness
  10. Drug-induced liver injury (diseases of the liver that are caused by physician-prescribed medications)

male:

  1. Fatigue (feeling of tiredness)
  2. Blood cholesterol increased
  3. Syncope (loss of consciousness with an inability to maintain postural tone)
  4. Cardiac failure
  5. Hydrocephalus (water on the brain)
  6. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  7. Pneumonia
  8. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  9. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  10. Gout (uric acid crystals building up in the body)

What are the common drug interactions of Citicoline and Aspirin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Hypopnoea (decrease in the breathing rate)
  2. Oxygen saturation decreased

20-29:

n/a

30-39:

  1. Cerebrovascular accident (sudden death of some brain cells due to lack of oxygen when the blood flow to the brain is impaired by blockage or rupture)
  2. Dizziness
  3. Headache (pain in head)
  4. Hemiparesis (weakness on one side of the body)
  5. Speech disorder

40-49:

  1. Cardiac failure
  2. Dizziness
  3. Headache (pain in head)
  4. Hydrocephalus (water on the brain)
  5. Subarachnoid haemorrhage (blood leaks into the space between two membranes that surround the brain)
  6. Syncope (loss of consciousness with an inability to maintain postural tone)
  7. Altered state of consciousness (altered state of mind)
  8. Anaemia (lack of blood)
  9. Aortic arteriosclerosis (hardening of the aortic arteries)
  10. Cardiomegaly (increased size of heart than normal)

50-59:

  1. International normalised ratio increased
  2. Joint swelling
  3. Loss of consciousness
  4. Mouth haemorrhage (bleeding from mouth)
  5. Pruritus (severe itching of the skin)
  6. Rash maculo-papular (red area on the skin that is covered with small confluent bumps)
  7. Skin discolouration (change of skin colour)
  8. Speech disorder
  9. Stupor (lack of critical cognitive function and level of consciousness)
  10. Varicose vein (veins that have become enlarged and tortuous)

60+:

  1. Fatigue (feeling of tiredness)
  2. Blood cholesterol increased
  3. Syncope (loss of consciousness with an inability to maintain postural tone)
  4. Vomiting
  5. Acute coronary syndrome (acute chest pain and other symptoms that happen because the heart does not get blood)
  6. Asthenia (weakness)
  7. Brain herniation (brain herniation is a potentially deadly side effect of very high intracranial pressure that occurs when a part of the brain is squeezed across structures within the skull)
  8. Dizziness
  9. Dyspnoea (difficult or laboured respiration)
  10. Loss of consciousness

What are the existing conditions these people have? *

  1. High Blood Pressure: 19 people, 25.33%
  2. Cerebral Infarction (less blood supply to brain resulting tissue damage): 17 people, 22.67%
  3. Diabetes: 17 people, 22.67%
  4. High Blood Cholesterol: 16 people, 21.33%
  5. Insomnia (sleeplessness): 15 people, 20.00%
  6. Enlarged Prostate: 13 people, 17.33%
  7. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 13 people, 17.33%
  8. Hypoalbuminaemia (levels of albumin in blood serum are abnormally low): 6 people, 8.00%
  9. Cardiac Failure: 5 people, 6.67%
  10. Joint Pain: 5 people, 6.67%

* Approximation only. Some reports may have incomplete information.

Do you take Citicoline and Aspirin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Citicoline and Aspirin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Citicoline:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Aspirin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Citicoline and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Aspirin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on citicoline and aspirin (the active ingredients of Citicoline and Aspirin, respectively), and Citicoline and Aspirin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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