Citicoline and Spironolactone drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Citicoline (citicoline) and Spironolactone (spironolactone). Common drug interactions include cardiac failure chronic among females and cerebral infarction among males.

The phase IV clinical study analyzes what interactions people have when they take Citicoline and Spironolactone. It is created by eHealthMe based on reports of 15 people who take the same drugs from the FDA, and is updated regularly.

What is Citicoline?

Citicoline has active ingredients of citicoline. eHealthMe is studying from 508 Citicoline users. Check the latest studies of Citicoline.

What is Spironolactone?

Spironolactone has active ingredients of spironolactone. It is often used in acne. eHealthMe is studying from 122,947 Spironolactone users. Check the latest studies of Spironolactone.

On Jul, 20, 2026

15 people who take Citicoline and Spironolactone together, and have interactions are studied.

Citicoline and Spironolactone drug interactions.

What are the common drug interactions of Citicoline and Spironolactone, by gender? *:

female:

Cardiac failure chronic
Haematemesis (vomiting of blood)
Cardiac arrest
Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
Embolic cerebral infarction (brain stroke due to obstruction of an artery)
General physical health deterioration (weak health status)
Haematuria (presence of blood in urine)
Haemorrhage subcutaneous (bleeding from skin)
Pain
Procedural haemorrhage (procedural bleeding)

male:

Cerebral infarction (less blood supply to brain resulting tissue damage)
Anuria (failure of the kidneys to produce urine)
Dizziness
Dysstasia (difficulty in standing)
Erythema (redness of the skin)
Face oedema (swelling of face)
Fall
Headache (pain in head)
Peripheral circulatory failure
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the common drug interactions of Citicoline and Spironolactone, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

n/a

60+:

Cardiac failure chronic
Cerebral infarction (less blood supply to brain resulting tissue damage)
Dizziness
Dysstasia (difficulty in standing)
Erythema (redness of the skin)
Face oedema (swelling of face)
Fall
Headache (pain in head)
Peripheral circulatory failure
Sepsis (a severe blood infection that can lead to organ failure and death)

What are the existing conditions these people have? *

Cardiac Failure: 7 people, 46.67%
Cerebral Infarction (less blood supply to brain resulting tissue damage): 6 people, 40.00%
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 5 people, 33.33%
High Blood Pressure: 5 people, 33.33%
Urination - Excessive Volume: 5 people, 33.33%
Gastric Disorder (disease of stomach): 5 people, 33.33%
Fever: 5 people, 33.33%
Low Density Lipoprotein Increased (cholesterol increased in blood): 5 people, 33.33%
Diabetes: 4 people, 26.67%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 4 people, 26.67%

* Approximation only. Some reports may have incomplete information.

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