Citrus and Gabapentin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Citrus (grapefruit) and Gabapentin (gabapentin). Common drug interactions include cough among females and cataract among males.

The phase IV clinical study analyzes what interactions people have when they take Citrus and Gabapentin. It is created by eHealthMe based on reports of 13 people who take the same drugs from the FDA, and is updated regularly.

What is Citrus?

Citrus has active ingredients of grapefruit. eHealthMe is studying from 201 Citrus users. Check the latest studies of Citrus.

What is Gabapentin?

Gabapentin has active ingredients of gabapentin. It is often used in neuralgia. eHealthMe is studying from 322,983 Gabapentin users. Check the latest studies of Gabapentin.



On Jul, 12, 2026

13 people who take Citrus and Gabapentin together, and have interactions are studied.

Citrus and Gabapentin drug interactions.

What are the common drug interactions of Citrus and Gabapentin, by gender? *:

female:

  1. Cough
  2. Stomatitis (inflammation of mucous membrane of mouth)
  3. Chest pain
  4. Headache (pain in head)
  5. Psoriasis (immune-mediated disease that affects the skin)
  6. Seasonal allergy (allergic condition due to certain season)
  7. Skin striae (irregular areas of skin that look like bands, stripes, or lines)
  8. Staphylococcal infection (an infection with staphylococcus bacteria)

male:

  1. Cataract (clouding of the lens inside the eye)
  2. Lip and/or oral cavity cancer (cancer of lip or mouth)
  3. Pruritus (severe itching of the skin)
  4. Skin haemorrhage (bleeding into skin)
  5. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  6. Spinal column stenosis (narrowing of spinal column)
  7. Type 2 diabetes mellitus
  8. Arteriosclerosis (thickening and hardening of arteries)
  9. Benign prostatic hyperplasia (benign enlargement of the prostate)
  10. Cough

What are the common drug interactions of Citrus and Gabapentin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

n/a

40-49:

n/a

50-59:

  1. Lumbar radiculopathy (radicular pain in the low back and legs)
  2. Osteoarthritis (a joint disease caused by cartilage loss in a joint)
  3. Psoriasis (immune-mediated disease that affects the skin)
  4. Skin striae (irregular areas of skin that look like bands, stripes, or lines)
  5. Sleep apnoea syndrome (a sleep-related disorder in which the effort to breathe is diminished or absent)
  6. Spinal column stenosis (narrowing of spinal column)
  7. Type 2 diabetes mellitus
  8. Arteriosclerosis (thickening and hardening of arteries)
  9. Benign prostatic hyperplasia (benign enlargement of the prostate)
  10. Delirium (wild excitement)

60+:

  1. Cataract (clouding of the lens inside the eye)
  2. Cough
  3. Lip and/or oral cavity cancer (cancer of lip or mouth)
  4. Stomatitis (inflammation of mucous membrane of mouth)
  5. Pruritus (severe itching of the skin)
  6. Skin haemorrhage (bleeding into skin)

What are the existing conditions these people have? *

  1. Immunodeficiency Common Variable: 4 people, 30.77%
  2. Breast Cancer Female: 2 people, 15.38%
  3. Hypersensitivity: 2 people, 15.38%
  4. Vasodilatation (widening of blood vessels resulting from relaxation of smooth muscle cells within the vessel walls): 1 person, 7.69%
  5. Haemostasis (stopping of bleeding): 1 person, 7.69%
  6. Bladder Neck Suspension: 1 person, 7.69%
  7. Constipation: 1 person, 7.69%
  8. Dermatitis Atopic (inflammatory, chronically relapsing, non-contagious and pruritic skin disorder): 1 person, 7.69%
  9. Diabetes: 1 person, 7.69%
  10. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 7.69%

* Approximation only. Some reports may have incomplete information.

Do you take Citrus and Gabapentin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Citrus and Gabapentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Citrus:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Gabapentin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Citrus and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Gabapentin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on grapefruit and gabapentin (the active ingredients of Citrus and Gabapentin, respectively), and Citrus and Gabapentin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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