Claravis and Zolpidem drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Claravis (isotretinoin) and Zolpidem (zolpidem tartrate). Common drug interactions include nausea among females and anxiety among males.
The phase IV clinical study analyzes what interactions people have when they take Claravis and Zolpidem. It is created by eHealthMe based on reports of 12 people who take the same drugs from the FDA, and is updated regularly.
What is Claravis?
Claravis has active ingredients of isotretinoin. It is often used in acne. eHealthMe is studying from 9,636 Claravis users. Check the latest studies of Claravis.
What is Zolpidem?
Zolpidem has active ingredients of zolpidem tartrate. It is often used in insomnia. eHealthMe is studying from 92,695 Zolpidem users. Check the latest studies of Zolpidem.
12 people who take Claravis and Zolpidem together, and have interactions are studied.

What are the common drug interactions of Claravis and Zolpidem, by gender? *:
female:
- Nausea (feeling of having an urge to vomit)
- Anhedonia (inability to experience pleasure from activities usually found enjoyable)
- Asthenia (weakness)
- Bipolar disorder (mood disorder)
- Depression
- Emotional distress
- Fatigue (feeling of tiredness)
- Fungal infection
- Injury
- Irritability
male:
- Anxiety
- Depression
- Femoroacetabular impingement (a condition affecting the hip joint in young and middle-aged adults)
- Joint stiffness
- Nephropathy (damage to or disease of a kidney)
- Osteonecrosis (death of bone)
- Renal injury (kidney injury)
- Skeletal injury (bone and supporting muscle injury)
- Soft tissue disorder (disease of soft tissue)
- Arthralgia (joint pain)
What are the common drug interactions of Claravis and Zolpidem, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
- Nausea (feeling of having an urge to vomit)
- Oropharyngeal pain
- Pyrexia (fever)
- Renal failure acute (rapid kidney dysfunction)
- Viral infection
- Vomiting
30-39:
- Bone disorder
- Bone loss
- Bursitis (inflammation of a bursa, typically one in the knee, elbow, or shoulder)
- Cartilage injury
- Femoroacetabular impingement (a condition affecting the hip joint in young and middle-aged adults)
- Joint stiffness
- Nephropathy (damage to or disease of a kidney)
- Osteonecrosis (death of bone)
- Renal injury (kidney injury)
- Skeletal injury (bone and supporting muscle injury)
40-49:
- Asthenia (weakness)
- Fatigue (feeling of tiredness)
- Nausea (feeling of having an urge to vomit)
- Night sweats (sweating in night)
50-59:
n/a
60+:
n/a
What are the existing conditions these people have? *
- Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 3 people, 25.00%
- Cataplexy (loss of muscle tone accompanied by full conscious awareness): 3 people, 25.00%
- Sleep Disorder: 3 people, 25.00%
- Hiv Infection: 2 people, 16.67%
- Stress And Anxiety: 1 person, 8.33%
- Headache (pain in head): 1 person, 8.33%
- Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 1 person, 8.33%
- Birth Control: 1 person, 8.33%
- Cardiac Disorder: 1 person, 8.33%
- Cough: 1 person, 8.33%
* Approximation only. Some reports may have incomplete information.
Do you take Claravis and Zolpidem?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Claravis and Zolpidem:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Claravis:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Zolpidem:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Claravis and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Zolpidem and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
- Hsu FG, Sheu MJ, Lin CL, Hsieh YW, Lai SW, "Use of Zolpidem and Risk of Acute Pyelonephritis in Women: A Population‐Based Case‐Control Study in Taiwan", The Journal of Clinical Pharmacology, 2017 Mar .
- Lin SC, Su YC, Huang YS, Lee CC, "Zolpidem increased cancer risk in patients with sleep disorder: A 3-year follow-up study", Journal of Medical Sciences, 2016 Mar .
- Sun Y, Lin CC, Lu CJ, Hsu CY, Kao CH, "Association between zolpidem and suicide: a nationwide population-based case-control study", InMayo Clinic Proceedings, 2016 Mar .
- Liao KF, Lin CL, Lai SW, Chen WC, "Zolpidem use associated with increased risk of pyogenic liver abscess: a case-control study in Taiwan", Medicine, 2015 Jan .
- Ersoy MA, Ersoy HT, "Manic symptoms associated with isotretinoin and methylphenidate combination: a case report", Klinik Psikofarmakoloji Bülteni-Bulletin of Clinical Psychopharmacology, 2014 Sep .
How the study uses the data?
The study uses data from the FDA. It is based on isotretinoin and zolpidem tartrate (the active ingredients of Claravis and Zolpidem, respectively), and Claravis and Zolpidem (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
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