Clarithromycin and Imuran drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clarithromycin (clarithromycin) and Imuran (azathioprine). Common drug interactions include dwarfism among females and drug hypersensitivity among males.

The phase IV clinical study analyzes what interactions people have when they take Clarithromycin and Imuran. It is created by eHealthMe based on reports of 55 people who take the same drugs from the FDA, and is updated regularly.

What is Clarithromycin?

Clarithromycin has active ingredients of clarithromycin. It is often used in sinusitis. eHealthMe is studying from 45,044 Clarithromycin users. Check the latest studies of Clarithromycin.

What is Imuran?

Imuran has active ingredients of azathioprine. It is often used in crohn's disease. eHealthMe is studying from 34,915 Imuran users. Check the latest studies of Imuran.

On Jul, 09, 2026

55 people who take Clarithromycin and Imuran together, and have interactions are studied.

Clarithromycin and Imuran drug interactions.

What are the common drug interactions of Clarithromycin and Imuran, by gender? *:

female:

Dwarfism (abnormally low stature)
Dyspnoea (difficult or laboured respiration)
Fatigue (feeling of tiredness)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)
Muscle spasms (muscle contraction)
Nasopharyngitis (inflammation of the nasopharynx)
Oedema peripheral (superficial swelling)
Pneumocystis carinii pneumonia (pneumonia occurring in infants or in persons with impaired immune systems)
Psoriasis (immune-mediated disease that affects the skin)
Pyrexia (fever)

male:

Drug hypersensitivity
Otitis media (inflammation of the middle ear)
Ascites (accumulation of fluid in the abdominal cavity)
Blood lactate dehydrogenase increased
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Cough
Cryoglobulins present
Deafness
Erythema (redness of the skin)
Joint swelling

What are the common drug interactions of Clarithromycin and Imuran, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Diabetes insipidus (diabetes caused by a deficiency of the pituitary hormone vasopressin, which regulates kidney function)
Dwarfism (abnormally low stature)
C-reactive protein increased
Growth hormone deficiency
Hypokalaemia (low potassium)
Hypophysitis (inflammation of the pituitary gland)
Lymphocytic hypophysitis (inflammation of the pituitary gland)
Pyrexia (fever)

10-19:

Ascites (accumulation of fluid in the abdominal cavity)
Cryoglobulins present
Leukopenia (less number of white blood cells in blood)
Vasculitis (inflammation of a blood vessel or blood vessels)
Autoimmune disorder (a condition in which the immune system attacks the body's normal substances and tissue)
Autoimmune hepatitis
Blood bilirubin increased
Cardiomyopathy (weakening of the heart muscle)
Chest tightness
Decreased activity

20-29:

Pneumothorax (the presence of air or gas in the cavity between the lungs and the chest wall, causing collapse of the lung)
Chylothorax (collection of lymph fluid around the lung)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)
Cytomegalovirus viraemia (cytomegalo virus in blood stream)
Enterocolitis (inflammation of the digestive tract, involving enteritis of the small intestine and colitis of the colon)
Hyperglycaemia (high blood sugar)
Lymphatic duct rupture (damage of lymph duct)
Pleural effusion (water on the lungs)
Pneumonia staphylococcal (pneumonia staphylococcal infections are usually caused by the organism staphylococcus aureus)
Renal impairment (severely reduced kidney function)

30-39:

Cholestasis (a condition where bile cannot flow from the liver to the duodenum)
Hepatic enzyme increased
Hepatic failure (liver failure)
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

40-49:

Dyspnoea (difficult or laboured respiration)
Dyspnoea exertional (breathlessness or shortness of breath)
Enterocolitis viral
Face oedema (swelling of face)
Fall
Fatigue (feeling of tiredness)
Headache (pain in head)
Heart rate irregular
Hypercholesterolaemia (high levels of cholesterol in the blood)
Intraocular pressure increased

50-59:

Drug hypersensitivity
Obliterative bronchiolitis (bronchiolar inflammation)
Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood cholesterol increased
Blood lactate dehydrogenase increased
Blood pressure increased
Depressed level of consciousness
Gamma-glutamyltransferase increased
Jaundice (a yellowish pigmentation of the skin, the conjunctival membranes)

60+:

Gamma-glutamyltransferase increased
Otitis media (inflammation of the middle ear)
Basal cell carcinoma (a skin cancer, it rarely metastasizes or kills)
Clostridium difficile colitis (inflammation of colon by clostridium difficile bacteria infection)
Osteoarthritis (a joint disease caused by cartilage loss in a joint)
Postmenopausal haemorrhage (post-menopausal bleeding)
Skin cancer
Squamous cell carcinoma of skin (a cancer of a kind of epithelial cell, the squamous cell. these cells are the main part of the epidermis of the skin)
Upper respiratory tract infection
Alanine aminotransferase increased

What are the existing conditions these people have? *

Osteoporosis (bones weak and more likely to break): 7 people, 12.73%
Immunodeficiency Common Variable: 7 people, 12.73%
Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 5 people, 9.09%
Ulcerative Colitis (inflammatory bowel disease (ibd). it causes swelling, ulcerations, and loss of function of the large intestine): 3 people, 5.45%
Systemic Lupus Erythematosus (an autoimmune disease, which means the body's immune system mistakenly, attacks healthy tissue): 3 people, 5.45%
Seasonal Allergy (allergic condition due to certain season): 3 people, 5.45%
Pulmonary Hypertension (increase in blood pressure in the lung artery): 3 people, 5.45%
Pachymeningitis (inflammation of the dura mater or outer membrane of the brain): 3 people, 5.45%
Mycobacterium Chelonae Infection (bacterial infection): 3 people, 5.45%
Interstitial Lung Disease: 3 people, 5.45%

* Approximation only. Some reports may have incomplete information.

Do you take Clarithromycin and Imuran?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously