Claritin-d and Bactrim drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Claritin-d (loratadine; pseudoephedrine sulfate) and Bactrim (sulfamethoxazole; trimethoprim). Common drug interactions include pain among females and overdose among males.

The phase IV clinical study analyzes what interactions people have when they take Claritin-d and Bactrim. It is created by eHealthMe based on reports of 22 people who take the same drugs from the FDA, and is updated regularly.

What is Claritin-d?

Claritin-d has active ingredients of loratadine; pseudoephedrine sulfate. It is often used in allergies. eHealthMe is studying from 7,055 Claritin-d users. Check the latest studies of Claritin-d.

What is Bactrim?

Bactrim has active ingredients of sulfamethoxazole; trimethoprim. It is often used in urinary tract infection. eHealthMe is studying from 89,117 Bactrim users. Check the latest studies of Bactrim.

On Jul, 12, 2026

22 people who take Claritin-d and Bactrim together, and have interactions are studied.

Claritin-d and Bactrim drug interactions.

What are the common drug interactions of Claritin-D and Bactrim, by gender? *:

female:

Pain
Aggression
Back pain
Breakthrough pain
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Cystic fibrosis (disease of the secretary glands)
Depression
Diverticulitis (digestive disease which involves the formation of pouches (diverticula) within the bowel wall)
Drug ineffective
Haematocrit decreased

male:

Overdose
Hepatic failure (liver failure)
Bone pain
Burning sensation
Cardiac failure
Cough
Death
Discomfort
Dysphagia (a condition in which swallowing is difficult or painful)
Erythema (redness of the skin)

What are the common drug interactions of Claritin-D and Bactrim, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

Death

20-29:

n/a

30-39:

Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Chronic sinusitis (long lasting inflammation of the paranasal sinuses)
Cystic fibrosis (disease of the secretary glands)
Haematocrit decreased
Haemoglobin decreased
Increased viscosity of nasal secretion
Injury
Osteopenia (a condition where bone mineral density is lower than normal)
Pain
Pancreatic insufficiency

40-49:

Aggression
Back pain
Blood glucose increased
Breakthrough pain
Depression
Drug ineffective
Intervertebral disc degeneration (spinal disc degeneration)
Pain
Suicide attempt
White blood cell count decreased

50-59:

Uveitis (inflammation of the uvea)
Burning sensation
Discomfort
Dysphagia (a condition in which swallowing is difficult or painful)
Erythema (redness of the skin)
Folliculitis (infection of hair root)
Foreign body trauma (injury by foreign particle)
Oesophageal obstruction (blockage of oesophagus)
Oesophageal stenosis (narrowing of oesophagus)
Oesophagitis (inflammation of oesophagus)

60+:

Overdose
Hepatic failure (liver failure)
Pyrexia (fever)
Respiratory tract congestion (blockage on respiratory system)
Hepatitis acute
Renal failure acute (rapid kidney dysfunction)
Acute hepatic failure
Rash generalised (rash on most of body parts)
Syncope (loss of consciousness with an inability to maintain postural tone)
Cardiac failure

What are the existing conditions these people have? *

Multiple Myeloma (cancer of the plasma cells): 6 people, 27.27%
Hypersensitivity: 5 people, 22.73%
Muscle Spasms (muscle contraction): 4 people, 18.18%
Insomnia (sleeplessness): 4 people, 18.18%
Type 2 Diabetes: 3 people, 13.64%
Gastritis (inflammation of stomach): 3 people, 13.64%
Atrial Fibrillation/flutter (atrial fibrillation and flutter are abnormal heart rhythms in which the atria, or upper chambers of the heart, are out of sync with the ventricles): 3 people, 13.64%
Depression: 3 people, 13.64%
Diabetic Retinal Oedema (excessive build-up of fluid in the retina due to diabetes): 3 people, 13.64%
Erection Problems: 3 people, 13.64%

* Approximation only. Some reports may have incomplete information.

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