Claritin and Metrocream drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Claritin (loratadine) and Metrocream (metronidazole). Common drug interactions include oedema peripheral among females and bladder cancer among males.

The phase IV clinical study analyzes what interactions people have when they take Claritin and Metrocream. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,316 Claritin users. Check the latest studies of Claritin.

What is Metrocream?

Metrocream has active ingredients of metronidazole. It is often used in rosacea. eHealthMe is studying from 458 Metrocream users. Check the latest studies of Metrocream.

On Aug, 11, 2026

16 people who take Claritin and Metrocream together, and have interactions are studied.

Claritin and Metrocream drug interactions.

What are the common drug interactions of Claritin and Metrocream, by gender? *:

female:

Oedema peripheral (superficial swelling)
Pruritus (severe itching of the skin)
Pain in extremity
Photopsia (presence of perceived flashes of light)
Abdominal pain lower
Abdominal pain upper
Adverse event
Alanine aminotransferase increased
Arthralgia (joint pain)
Back pain

male:

Bladder cancer
Bladder hypertrophy (bladder overgrowth- increase in cell size)
Flank pain (a distressing sensation experienced around the lower back and the upper abdomen)
Haematocrit decreased
Haemoglobin decreased
Lymphocyte percentage decreased
Mean cell haemoglobin concentration decreased (less concentration of haemoglobin in a given volume of packed red blood cells)
Mean platelet volume increased (more than normal average size of platelet cells in blood)
Red blood cell count decreased

What are the common drug interactions of Claritin and Metrocream, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

Alanine aminotransferase increased
Diarrhoea

40-49:

Abdominal pain lower
Abdominal pain upper
Arthralgia (joint pain)
Bladder pain
Burning sensation
Chest pain
Crepitations (noises are produced by the rubbing of parts one against the other)
Depersonalisation
Diarrhoea
Dissociation

50-59:

Cough
Pruritus (severe itching of the skin)

60+:

Adverse event
Bladder cancer
Flushing (the warm, red condition of human skin)
Haematocrit decreased
Haemoglobin decreased
Hypotension (abnormally low blood pressure)
Infection
Lymphocyte percentage decreased
Mean cell haemoglobin concentration decreased (less concentration of haemoglobin in a given volume of packed red blood cells)
Mean platelet volume increased (more than normal average size of platelet cells in blood)

What are the existing conditions these people have? *

Hypersensitivity: 4 people, 25.00%
Wheezing (a high-pitched whistling sound made while you breath): 3 people, 18.75%
Nausea (feeling of having an urge to vomit): 3 people, 18.75%
Cough: 3 people, 18.75%
Pain: 3 people, 18.75%
Psoriasis (immune-mediated disease that affects the skin): 2 people, 12.50%
Itching: 2 people, 12.50%
Urticaria (rash of round, red welts on the skin that itch intensely): 2 people, 12.50%
Fungal Infection: 2 people, 12.50%
Nausea And Vomiting: 2 people, 12.50%

* Approximation only. Some reports may have incomplete information.

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