Claritin and Polaramine drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Claritin (loratadine) and Polaramine (dexchlorpheniramine maleate). Common drug interactions include staphylococcal infection among females and alopecia among males.

The phase IV clinical study analyzes what interactions people have when they take Claritin and Polaramine. It is created by eHealthMe based on reports of 54 people who take the same drugs from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,315 Claritin users. Check the latest studies of Claritin.

What is Polaramine?

Polaramine has active ingredients of dexchlorpheniramine maleate. It is often used in allergic rhinitis. eHealthMe is studying from 10,531 Polaramine users. Check the latest studies of Polaramine.

On Jul, 11, 2026

54 people who take Claritin and Polaramine together, and have interactions are studied.

Claritin and Polaramine drug interactions.

What are the common drug interactions of Claritin and Polaramine, by gender? *:

female:

Staphylococcal infection (an infection with staphylococcus bacteria)
Stevens-johnson syndrome (an immune-complex-mediated hypersensitivity disorder. it ranges from mild skin and mucous membrane lesions to a severe)
Thrombocytopenia (decrease of platelets in blood)
Toxic skin eruption (skin breakdown due to toxic substance)
Urticaria (rash of round, red welts on the skin that itch intensely)
Myositis (inflammation of the muscles)
Abdominal pain
Alanine aminotransferase increased
Anaphylactic shock (severe and rapid and sometimes fatal hypersensitivity reaction to a substance)
Aspartate aminotransferase increased

male:

Alopecia (absence of hair from areas of the body)
Asthenia (weakness)
Asthma
Febrile neutropenia (fever with reduced white blood cells)
Kidney transplant rejection
Pancytopenia (medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets)
Plasma cell myeloma (cancer that begins in plasma cells)
Platelet count decreased
Pyrexia (fever)
Weight increased

What are the common drug interactions of Claritin and Polaramine, by age (0-1 to 60+)? *:

0-1:

Drug eruption (adverse drug reaction of the skin)

2-9:

Insomnia (sleeplessness)
Loss of consciousness
Lymphocyte count increased
Monocyte count increased
Neutrophil count increased (excess than normal number of neutrophil a type of blood cell)
Pulse absent
Restlessness (not able to rest)
Vomiting
White blood cell count increased
Tremor (trembling or shaking movements in one or more parts of your body)

10-19:

Anaemia (lack of blood)
Decreased appetite
Diarrhoea
Febrile neutropenia (fever with reduced white blood cells)
Gastric mucosal lesion (lesion of stomach mucous membrane)
Headache (pain in head)
Hyperbilirubinaemia (excess of bilirubin in the blood)
Nausea (feeling of having an urge to vomit)
Neutropenia (an abnormally low number of neutrophils)
Platelet count decreased

20-29:

n/a

30-39:

n/a

40-49:

Alanine aminotransferase increased
Aspartate aminotransferase increased
Blood alkaline phosphatase increased
Cystitis (inflammation of the wall of the bladder)
Dysuria (painful or difficult urination)
Gamma-glutamyltransferase increased
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Intracranial tumour haemorrhage (bleeding tumour in brain)
Liver disorder (liver diseases)
Metastases to central nervous system (cancer spreads to central nervous system)

50-59:

Erythema (redness of the skin)
Pyrexia (fever)
Anaemia (lack of blood)
Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
Face oedema (swelling of face)
Inflammation
Leukopenia (less number of white blood cells in blood)
Pruritus generalised (generalized itching)
Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
Vomiting

60+:

Alopecia (absence of hair from areas of the body)
Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
Anaemia (lack of blood)
Arthralgia (joint pain)
Diarrhoea
Dyspnoea (difficult or laboured respiration)
Escherichia urinary tract infection (urinary tract infection by escherichia coli)
Febrile neutropenia (fever with reduced white blood cells)
Flushing (the warm, red condition of human skin)
Fungal infection

What are the existing conditions these people have? *

High Blood Pressure: 9 people, 16.67%
Itching: 6 people, 11.11%
Gastritis (inflammation of stomach): 6 people, 11.11%
Osteoporosis (bones weak and more likely to break): 5 people, 9.26%
Insomnia (sleeplessness): 5 people, 9.26%
Thrombophlebitis (swelling (inflammation) of a vein caused by a blood clot): 4 people, 7.41%
Spinal Osteoarthritis (joint cartilage loss in spine): 4 people, 7.41%
Pharyngolaryngeal Pain: 4 people, 7.41%
Swelling Face: 3 people, 5.56%
Hepatic Neoplasm Malignant (liver cancer): 3 people, 5.56%

* Approximation only. Some reports may have incomplete information.

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