Claritin and Rapaflo drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Claritin (loratadine) and Rapaflo (silodosin). Common drug interactions include drug ineffective among females and fall among males.

The phase IV clinical study analyzes what interactions people have when they take Claritin and Rapaflo. It is created by eHealthMe based on reports of 39 people who take the same drugs from the FDA, and is updated regularly.

What is Claritin?

Claritin has active ingredients of loratadine. It is often used in allergies. eHealthMe is studying from 77,315 Claritin users. Check the latest studies of Claritin.

What is Rapaflo?

Rapaflo has active ingredients of silodosin. It is often used in prostate examination abnormal. eHealthMe is studying from 3,929 Rapaflo users. Check the latest studies of Rapaflo.



On Jul, 13, 2026

39 people who take Claritin and Rapaflo together, and have interactions are studied.

Claritin and Rapaflo drug interactions.

What are the common drug interactions of Claritin and Rapaflo, by gender? *:

female:

  1. Drug ineffective
  2. Suicidal ideation

male:

  1. Fall
  2. Drug ineffective
  3. Leukocytosis (increased white blood cells)
  4. Rib fracture
  5. Somnolence (a state of near-sleep, a strong desire for sleep)
  6. Affective disorder (mental disorder)
  7. Chronic kidney disease
  8. Concussion (short loss of normal brain function in response to a head injury)
  9. Dizziness
  10. Feeling hot

What are the common drug interactions of Claritin and Rapaflo, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Depression

30-39:

n/a

40-49:

  1. Agitation (state of anxiety or nervous excitement)
  2. Ammonia increased
  3. Anger
  4. Arterial thrombosis limb (formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system-limb)
  5. Emotional disorder
  6. Onychomadesis (a periodic idiopathic shedding of the nails)
  7. Skin discolouration (change of skin colour)
  8. Drug ineffective
  9. Affective disorder (mental disorder)
  10. Depression

50-59:

n/a

60+:

  1. Fatigue (feeling of tiredness)
  2. Leukocytosis (increased white blood cells)
  3. Renal failure (kidney dysfunction)
  4. Renal injury (kidney injury)
  5. Seizure (abnormal excessive or synchronous neuronal activity in the brain)
  6. Weight decreased
  7. White blood cell count decreased
  8. Drug effect delayed
  9. Drug ineffective
  10. Gait disturbance

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 10 people, 25.64%
  2. High Blood Pressure: 7 people, 17.95%
  3. Back Pain: 5 people, 12.82%
  4. Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 4 people, 10.26%
  5. Bladder Disorder: 4 people, 10.26%
  6. Multiple Myeloma (cancer of the plasma cells): 4 people, 10.26%
  7. Bladder Obstruction: 3 people, 7.69%
  8. Nasal Congestion (blockage of the nasal passages usually due to membranes lining the nose becoming swollen from inflamed blood vessels): 3 people, 7.69%
  9. Cardiac Failure: 2 people, 5.13%
  10. Depression: 2 people, 5.13%

* Approximation only. Some reports may have incomplete information.

Do you take Claritin and Rapaflo?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously



Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Claritin and Rapaflo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Claritin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Rapaflo:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Claritin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Rapaflo and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on loratadine and silodosin (the active ingredients of Claritin and Rapaflo, respectively), and Claritin and Rapaflo (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



Recent studies on eHealthMe: