Clexane and Topamax drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clexane (enoxaparin sodium) and Topamax (topiramate). Common drug interactions include deafness among females and confusional state among males.
The phase IV clinical study analyzes what interactions people have when they take Clexane and Topamax. It is created by eHealthMe based on reports of 11 people who take the same drugs from the FDA, and is updated regularly.
What is Clexane?
Clexane has active ingredients of enoxaparin sodium. eHealthMe is studying from 14,679 Clexane users. Check the latest studies of Clexane.
What is Topamax?
Topamax has active ingredients of topiramate. It is often used in migraine. eHealthMe is studying from 58,954 Topamax users. Check the latest studies of Topamax.
11 people who take Clexane and Topamax together, and have interactions are studied.

What are the common drug interactions of Clexane and Topamax, by gender? *:
female:
- Deafness
- Hypokalaemia (low potassium)
- Nasopharyngitis (inflammation of the nasopharynx)
male:
- Confusional state
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Acute myocardial infarction (acute heart attack)
- Balance disorder
- Cerebral haemorrhage (bleeding within the brain)
- Constipation
- Epistaxis (bleed from the nose)
- Face injury
- Fall
- Gait disturbance
What are the common drug interactions of Clexane and Topamax, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
- Nervous system disorder (a general class of medical conditions affecting the nervous system)
- Status epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure)
50-59:
- Acute myeloid leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts)
- Pulmonary embolism (blockage of the main artery of the lung)
- Ammonia increased
- Complex partial seizures (epileptic seizure)
- Depressed level of consciousness
- Eating disorder
- Encephalitis (inflammation of the brain)
- General physical health deterioration (weak health status)
- Hepatic enzyme increased
- Hypokalaemia (low potassium)
60+:
- Confusional state
- Aggression
- Constipation
- Depressed level of consciousness
- Epistaxis (bleed from the nose)
- Face injury
- Fall
- Gait disturbance
- Pyrexia (fever)
- Tachypnoea (a condition of rapid breathing over 20 per minute)
What are the existing conditions these people have? *
- Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 5 people, 45.45%
- Status Epilepticus (a life-threatening condition in which the brain is in a state of persistent seizure): 1 person, 9.09%
- Rheumatoid Arthritis (a chronic progressive disease causing inflammation in the joints): 1 person, 9.09%
- Psoriatic Arthropathy (inflammation of the skin and joints with kin condition which typically causes patches (plaques) of red, scaly skin to develop): 1 person, 9.09%
- Muscle Spasms (muscle contraction): 1 person, 9.09%
- Multiple Myeloma (cancer of the plasma cells): 1 person, 9.09%
- Hypothyroidism (abnormally low activity of the thyroid gland, resulting in retardation of growth and mental development): 1 person, 9.09%
- Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body): 1 person, 9.09%
- Ankylosing Spondylitis (type of arthritis affecting the spine): 1 person, 9.09%
- Amyloidosis (a tumour within which amyloid is produced): 1 person, 9.09%
* Approximation only. Some reports may have incomplete information.
Do you take Clexane and Topamax?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Clexane and Topamax:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clexane:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Topamax:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clexane and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Topamax and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
- Baloch M, Siddiqui MA, "Topiramate induced sudden loss of vision", JPMA, 2012 Oct .
- Kocamaz, M., & Karadag, O., "Topiramate-Induced Acute Myopia, Diplopia, and Photosensitivity: A Case Report", Beyoglu Eye Journal, 2019 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on enoxaparin sodium and topiramate (the active ingredients of Clexane and Topamax, respectively), and Clexane and Topamax (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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