Clindamycin phosphate and Melatonin drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clindamycin phosphate (clindamycin phosphate) and Melatonin (melatonin). Common drug interactions include lacrimation increased among females and dry mouth among males.

The phase IV clinical study analyzes what interactions people have when they take Clindamycin phosphate and Melatonin. It is created by eHealthMe based on reports of 66 people who take the same drugs from the FDA, and is updated regularly.

What is Clindamycin phosphate?

Clindamycin phosphate has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 4,216 Clindamycin phosphate users. Check the latest studies of Clindamycin phosphate.

What is Melatonin?

Melatonin has active ingredients of melatonin. It is often used in insomnia. eHealthMe is studying from 56,212 Melatonin users. Check the latest studies of Melatonin.



On Aug, 08, 2026

66 people who take Clindamycin phosphate and Melatonin together, and have interactions are studied.

Clindamycin phosphate and Melatonin drug interactions.

What are the common drug interactions of Clindamycin Phosphate and Melatonin, by gender? *:

female:

  1. Lacrimation increased
  2. Abdominal distension
  3. Abdominal pain
  4. Abdominal pain upper
  5. Abnormal sleep-related event
  6. Adrenal disorder
  7. Affective disorder (mental disorder)
  8. Alopecia (absence of hair from areas of the body)
  9. Aphasia (damage to the parts of the brain that control language)
  10. Arthralgia (joint pain)

male:

  1. Dry mouth
  2. Fatigue (feeling of tiredness)
  3. Chest pain
  4. Constipation
  5. Death
  6. Diarrhoea
  7. Disease progression
  8. Epistaxis (bleed from the nose)
  9. Headache (pain in head)
  10. Heart rate decreased

What are the common drug interactions of Clindamycin Phosphate and Melatonin, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

  1. Burning sensation
  2. Erythema (redness of the skin)
  3. Pruritus (severe itching of the skin)
  4. Rash
  5. Wisdom teeth removal
  6. Affective disorder (mental disorder)
  7. Hospitalisation
  8. Ileal stenosis (obstruction in the ileal)
  9. Infusion site hypersensitivity

20-29:

  1. Adrenal disorder
  2. Anxiety
  3. Autoimmune thyroiditis (form of thyroiditis associated with an autoimmune disease)
  4. Coeliac disease (simple food intolerance)
  5. Death
  6. Depression
  7. Gastrointestinal disorder (functional problems of gastrointestinal tract)

30-39:

  1. Nausea (feeling of having an urge to vomit)
  2. Pain in extremity
  3. Rash
  4. Abdominal pain upper
  5. Abnormal sleep-related event
  6. Anxiety
  7. Asthenia (weakness)
  8. Attention deficit hyperactivity disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness)
  9. Back pain
  10. Cataract (clouding of the lens inside the eye)

40-49:

  1. Anxiety
  2. Biliary colic
  3. Blood pressure increased
  4. Diarrhoea
  5. Drug intolerance (drug sensitivity)
  6. Infusion site haemorrhage (bleeding from infusion site)
  7. Infusion site pain
  8. Nausea (feeling of having an urge to vomit)
  9. Poor venous access
  10. Post procedural complication

50-59:

  1. Rash
  2. Anaemia (lack of blood)
  3. Asthenia (weakness)
  4. Constipation
  5. Diarrhoea
  6. Disease progression
  7. Dry mouth
  8. Epistaxis (bleed from the nose)
  9. Fatigue (feeling of tiredness)
  10. Folliculitis (infection of hair root)

60+:

  1. Rash
  2. Atypical pneumonia (acute respiratory disease marked by high fever and coughing)
  3. Nasopharyngitis (inflammation of the nasopharynx)
  4. Neoplasm malignant (cancer tumour)
  5. Neutrophil count decreased (less than normal number of neutrophil a type of blood cell)
  6. Pain in extremity
  7. Palpitations (feelings or sensations that your heart is pounding or racing)
  8. Pneumonia
  9. Sinusitis (inflammation of sinus)
  10. Skin wrinkling (wrinkle on skin)

What are the existing conditions these people have? *

  1. Narcolepsy (brain's inability to regulate sleep-wake cycles normally): 20 people, 30.30%
  2. Cataplexy (loss of muscle tone accompanied by full conscious awareness): 16 people, 24.24%
  3. Immunodeficiency Common Variable: 12 people, 18.18%
  4. Primary Immunodeficiency Syndrome: 5 people, 7.58%
  5. Arthritis (form of joint disorder that involves inflammation of one or more joints): 5 people, 7.58%
  6. Polycythaemia Vera (blood disorder in which the bone marrow makes too many red blood cells): 4 people, 6.06%
  7. Acne (skin problems that cause pimples): 4 people, 6.06%

* Approximation only. Some reports may have incomplete information.

Do you take Clindamycin phosphate and Melatonin?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Clindamycin phosphate and Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clindamycin phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Melatonin:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clindamycin phosphate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Melatonin and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on clindamycin phosphate and melatonin (the active ingredients of Clindamycin phosphate and Melatonin, respectively), and Clindamycin phosphate and Melatonin (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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