Clindamycin phosphate and Nexium drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clindamycin phosphate (clindamycin phosphate) and Nexium (esomeprazole magnesium). Common drug interactions include squamous cell carcinoma among females and chronic kidney disease among males.

The phase IV clinical study analyzes what interactions people have when they take Clindamycin phosphate and Nexium. It is created by eHealthMe based on reports of 82 people who take the same drugs from the FDA, and is updated regularly.

What is Clindamycin phosphate?

Clindamycin phosphate has active ingredients of clindamycin phosphate. It is often used in infection. eHealthMe is studying from 4,216 Clindamycin phosphate users. Check the latest studies of Clindamycin phosphate.

What is Nexium?

Nexium has active ingredients of esomeprazole magnesium. It is often used in gastroesophageal reflux disease. eHealthMe is studying from 245,678 Nexium users. Check the latest studies of Nexium.



On Aug, 04, 2026

82 people who take Clindamycin phosphate and Nexium together, and have interactions are studied.

Clindamycin phosphate and Nexium drug interactions.

What are the common drug interactions of Clindamycin Phosphate and Nexium, by gender? *:

female:

  1. Squamous cell carcinoma (a cancer of a kind of epithelial cell)
  2. Thyroid mass
  3. Vertigo
  4. Fall
  5. Abdominal pain
  6. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  7. Arthralgia (joint pain)
  8. Asthma
  9. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  10. Choking (mechanical obstruction of the flow of air from the environment into the lungs)

male:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Sinusitis (inflammation of sinus)
  4. Back disorder
  5. Infusion related reaction
  6. Oral surgery
  7. Thrombocytopenia (decrease of platelets in blood)
  8. Vomiting
  9. Fatigue (feeling of tiredness)
  10. Central nervous system lesion (an abnormality in tissue of brain or spinal cord)

What are the common drug interactions of Clindamycin Phosphate and Nexium, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

  1. Pain
  2. Drug hypersensitivity
  3. Dyspnoea (difficult or laboured respiration)
  4. Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
  5. Choking (mechanical obstruction of the flow of air from the environment into the lungs)
  6. Hypoaesthesia (reduced sense of touch or sensation)
  7. Lip swelling
  8. Pyrexia (fever)
  9. Swelling face
  10. Swollen tongue (swelling of tongue)

30-39:

  1. Arthralgia (joint pain)
  2. Blood testosterone increased
  3. Cold sweat
  4. Disease complication
  5. Fatigue (feeling of tiredness)
  6. Headache (pain in head)
  7. Immune system disorder
  8. Myalgia (muscle pain)
  9. Nausea (feeling of having an urge to vomit)
  10. Breast cancer metastatic

40-49:

  1. Chronic kidney disease
  2. Nephrogenic anaemia (anaemia due to kidney disease)
  3. Renal disorder (kidney disease)
  4. Renal failure (kidney dysfunction)
  5. Dermatitis bullous (inflammation of the skin characterized by the presence of bullae which are filled with fluid)
  6. Toxic epidermal necrolysis (a rare, life-threatening skin condition that is usually caused by a reaction to drugs causes wide spread skin destruction)
  7. Acute respiratory distress syndrome
  8. Anhedonia (inability to experience pleasure from activities usually found enjoyable)
  9. Anxiety
  10. Arthralgia (joint pain)

50-59:

  1. Cardiac flutter (abnormal heart rhythm)
  2. Dehydration (dryness resulting from the removal of water)
  3. Foot fracture
  4. Infusion site haemorrhage (bleeding from infusion site)
  5. Ligament sprain (ligament stretched)
  6. Limb injury
  7. Pulmonary embolism (blockage of the main artery of the lung)
  8. Salivary gland mass
  9. Therapeutic response decreased (less preventive response)
  10. Anxiety

60+:

  1. Chronic kidney disease
  2. Renal failure (kidney dysfunction)
  3. Ear infection
  4. Fungal infection
  5. Hypertonic bladder (bladder-storage function that causes a sudden urge to urinate)
  6. Liver abscess (pus in liver)
  7. Pyrexia (fever)
  8. Renal injury (kidney injury)
  9. Upper respiratory tract inflammation
  10. Urinary tract infection

What are the existing conditions these people have? *

  1. Insomnia (sleeplessness): 15 people, 18.29%
  2. Immunodeficiency Common Variable: 11 people, 13.41%
  3. High Blood Cholesterol: 9 people, 10.98%
  4. High Blood Pressure: 7 people, 8.54%
  5. Stress And Anxiety: 6 people, 7.32%
  6. Asthma: 6 people, 7.32%
  7. Pain: 5 people, 6.10%
  8. Humoral Immune Defect (impairment of humoral immunity): 5 people, 6.10%
  9. Diabetes: 5 people, 6.10%
  10. Depression: 5 people, 6.10%

* Approximation only. Some reports may have incomplete information.

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Clindamycin phosphate and Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clindamycin phosphate:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Nexium:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clindamycin phosphate and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Nexium and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Related publications that referenced our studies


How the study uses the data?

The study uses data from the FDA. It is based on clindamycin phosphate and esomeprazole magnesium (the active ingredients of Clindamycin phosphate and Nexium, respectively), and Clindamycin phosphate and Nexium (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.



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