Clobazam and Donepezil drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clobazam (clobazam) and Donepezil (donepezil hydrochloride). Common drug interactions include dysphagia among females and ataxia among males.

The phase IV clinical study analyzes what interactions people have when they take Clobazam and Donepezil. It is created by eHealthMe based on reports of 36 people who take the same drugs from the FDA, and is updated regularly.

What is Clobazam?

Clobazam has active ingredients of clobazam. eHealthMe is studying from 14,399 Clobazam users. Check the latest studies of Clobazam.

What is Donepezil?

Donepezil has active ingredients of donepezil hydrochloride. It is often used in dementia. eHealthMe is studying from 24,564 Donepezil users. Check the latest studies of Donepezil.



On Jul, 11, 2026

36 people who take Clobazam and Donepezil together, and have interactions are studied.

Clobazam and Donepezil drug interactions.

What are the common drug interactions of Clobazam and Donepezil, by gender? *:

female:

  1. Dysphagia (a condition in which swallowing is difficult or painful)
  2. Hypokinesia (decreased bodily movement)
  3. Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
  4. Muscle rigidity (muscle stiffness)
  5. Pyrexia (fever)
  6. Speech disorder
  7. Tremor (trembling or shaking movements in one or more parts of your body)
  8. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  9. Asthenia (weakness)
  10. Oropharyngeal pain

male:

  1. Ataxia (loss of full control of bodily movements)
  2. Fall
  3. Muscle rigidity (muscle stiffness)
  4. Somnolence (a state of near-sleep, a strong desire for sleep)
  5. Unresponsive to stimuli
  6. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  7. Bradycardia (abnormally slow heart action)
  8. Circulatory collapse

What are the common drug interactions of Clobazam and Donepezil, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

n/a

10-19:

n/a

20-29:

n/a

30-39:

  1. Ataxia (loss of full control of bodily movements)
  2. Atonic seizures (minor type of seizure)
  3. Myoclonic epilepsy (type of epilepsy with quick little jerks of the arms, shoulder, or occasionally the legs)
  4. Seizure (abnormal excessive or synchronous neuronal activity in the brain)

40-49:

n/a

50-59:

n/a

60+:

  1. Neuroleptic malignant syndrome (a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic agents)
  2. Muscle rigidity (muscle stiffness)
  3. Pyrexia (fever)
  4. Speech disorder
  5. Tremor (trembling or shaking movements in one or more parts of your body)
  6. Urinary incontinence (inability to control the flow of urine and involuntary urination)
  7. Atrial fibrillation (fibrillation of the muscles of the atria of the heart)
  8. Bradycardia (abnormally slow heart action)
  9. Circulatory collapse
  10. Ataxia (loss of full control of bodily movements)

What are the existing conditions these people have? *

  1. Seizures (abnormal excessive or synchronous neuronal activity in the brain): 15 people, 41.67%
  2. Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 15 people, 41.67%
  3. Memory Loss: 7 people, 19.44%
  4. High Blood Pressure: 3 people, 8.33%
  5. Psoriasis (immune-mediated disease that affects the skin): 2 people, 5.56%
  6. Epilepsy (common and diverse set of chronic neurological disorders characterized by seizures): 2 people, 5.56%

* Approximation only. Some reports may have incomplete information.

Do you take Clobazam and Donepezil?

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Related studies:

Effectiveness of, side effects of, and alternative drugs to the 2 drugs:

Browse all drug interactions of Clobazam and Donepezil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Sub-studies by gender and age:

Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+

Browse all side effects of Clobazam:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all side effects of Donepezil:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Clobazam and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

Browse all interactions between Donepezil and drugs from A to Z:

a b c d e f g h i j k l m n o p q r s t u v w x y z

How the study uses the data?

The study uses data from the FDA. It is based on clobazam and donepezil hydrochloride (the active ingredients of Clobazam and Donepezil, respectively), and Clobazam and Donepezil (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.

How to use the study?

DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.

Who is eHealthMe?

With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).

WARNING, DISCLAIMER, USE FOR PUBLICATION

WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.

DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.

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