Iclusig and Lexapro drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Iclusig (ponatinib hydrochloride) and Lexapro (escitalopram oxalate). Common drug interactions include headache among females and headache among males.
The phase IV clinical study analyzes what interactions people have when they take Iclusig and Lexapro. It is created by eHealthMe based on reports of 29 people who take the same drugs from the FDA, and is updated regularly.
What is Iclusig?
Iclusig has active ingredients of ponatinib hydrochloride. eHealthMe is studying from 6,109 Iclusig users. Check the latest studies of Iclusig.
What is Lexapro?
Lexapro has active ingredients of escitalopram oxalate. It is often used in depression. eHealthMe is studying from 91,464 Lexapro users. Check the latest studies of Lexapro.
29 people who take Iclusig and Lexapro together, and have interactions are studied.

What are the common drug interactions of Iclusig and Lexapro, by gender? *:
female:
- Headache (pain in head)
- Asthenia (weakness)
- Pneumonia
- Abdominal pain upper
- Dry skin
- Nausea (feeling of having an urge to vomit)
- Vision blurred
- Dizziness
- Dyskinesia (abnormality or impairment of voluntary movement)
- Fatigue (feeling of tiredness)
male:
- Headache (pain in head)
- Arachnoiditis (neuropathic disease caused by inflammation of the arachnoid)
- Hypokalaemia (low potassium)
- Immunodeficiency
- Oedema (fluid collection in tissue)
- Pain
- Pneumonia
- Pyrexia (fever)
- Skin lesion
- Somnolence (a state of near-sleep, a strong desire for sleep)
What are the common drug interactions of Iclusig and Lexapro, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
- Pain in extremity
20-29:
n/a
30-39:
n/a
40-49:
- Death
- Diabetic ketoacidosis (diabetic ketoacidosis (dka) is high concentrations of ketone bodies)
- Fluid overload (too much fluid in the blood)
- Hypophagia (reduced food intake)
- Infection
- Stem cell transplant
- Tachycardia (a heart rate that exceeds the range of 100 beats/min)
- Constipation
50-59:
- Fatigue (feeling of tiredness)
- Headache (pain in head)
- Arachnoiditis (neuropathic disease caused by inflammation of the arachnoid)
- Cerebral infarction (less blood supply to brain resulting tissue damage)
- Confusional state
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Dysarthria (speech disorder)
- Fall
- Hepatic enzyme increased
- Hypercalcaemia (elevated calcium (ca+) level in the blood)
60+:
- Abdominal pain upper
- Headache (pain in head)
- Gallbladder disorder
- Heart rate increased
- Malaise (a feeling of general discomfort or uneasiness)
- Panic attack
- Pneumonia
- Post procedural infection
- Rash generalised (rash on most of body parts)
- Respiratory rate increased (excess breathing rate/min)
What are the existing conditions these people have? *
- Chronic Myeloid Leukaemia (long lasting type of cancer that starts in the blood-forming cells of the bone marrow and invades the blood): 19 people, 65.52%
- Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 8 people, 27.59%
- Pain: 7 people, 24.14%
- High Blood Pressure: 6 people, 20.69%
- Insomnia (sleeplessness): 5 people, 17.24%
- Sleep Disorder: 4 people, 13.79%
- Nausea (feeling of having an urge to vomit): 4 people, 13.79%
- Joint Pain: 3 people, 10.34%
- High Blood Cholesterol: 3 people, 10.34%
- Urinary Tract Infection: 2 people, 6.90%
* Approximation only. Some reports may have incomplete information.
Do you take Iclusig and Lexapro?
- Personalize this study to your gender, age, symptoms and drugs
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
Browse all drug interactions of Iclusig and Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Iclusig:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Lexapro:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Iclusig and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Lexapro and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
- O’Brien FE, O’Connor RM, Clarke G, Donovan MD, Dinan TG, Griffin BT, Cryan JF, "The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram", Behavioural brain research, 2014 Mar .
How the study uses the data?
The study uses data from the FDA. It is based on ponatinib hydrochloride and escitalopram oxalate (the active ingredients of Iclusig and Lexapro, respectively), and Iclusig and Lexapro (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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