Clolar and Ambisome drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clolar (clofarabine) and Ambisome (amphotericin b). Common drug interactions include hallucination among females and aspergillosis among males.

The phase IV clinical study analyzes what interactions people have when they take Clolar and Ambisome. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Clolar?

Clolar has active ingredients of clofarabine. eHealthMe is studying from 1,093 Clolar users. Check the latest studies of Clolar.

What is Ambisome?

Ambisome has active ingredients of amphotericin b. eHealthMe is studying from 7,934 Ambisome users. Check the latest studies of Ambisome.

On Jul, 20, 2026

19 people who take Clolar and Ambisome together, and have interactions are studied.

What are the common drug interactions of Clolar and Ambisome, by gender? *:

female:

Hallucination (an experience involving the perception of something not present)
Lung consolidation (a condition whereby the lung tissues solidify because of the accumulation of solid and liquid material in the air spaces)
Metabolic acidosis (body produces too much acid, or when the kidneys are not removing enough acid from the body)
Platelet count decreased
Renal failure acute (rapid kidney dysfunction)
Staphylococcal infection (an infection with staphylococcus bacteria)
Blood alkaline phosphatase increased
Gamma-glutamyltransferase increased
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Lymphopenia (an abnormally low level of lymphocytes in the blood)

male:

Aspergillosis (an infection caused by a fungus called aspergillus)
Hypotension (abnormally low blood pressure)
Respiratory failure (inadequate gas exchange by the respiratory system)
Small intestinal obstruction (blockage in small intestine)
Cardiac arrest
Coagulopathy (blood's ability to clot is impaired)
Depressed level of consciousness
Diarrhoea
Diastolic dysfunction
Drug toxicity

What are the common drug interactions of Clolar and Ambisome, by age (0-1 to 60+)? *:

0-1:

n/a

2-9:

Aspergillosis (an infection caused by a fungus called aspergillus)
Lung neoplasm (tumour of lung)
Neutropenia (an abnormally low number of neutrophils)
Osteomyelitis (infection of bone)
Pain in extremity
Paraesthesia (sensation of tingling, tickling, prickling, pricking, or burning of a person's skin with no apparent long-term physical effect)
Pyrexia (fever)

10-19:

Weight decreased
Acute graft versus host disease (acute complication following an allogeneic tissue/blood transplant)
Alanine aminotransferase increased
Alpha haemolytic streptococcal infection (infections with alpha-haemolytic strep bacteria are common; many strains live naturally in humans)
Aspartate aminotransferase increased
Aspergillosis (an infection caused by a fungus called aspergillus)
Blood culture positive
Blood disorder
Bronchopulmonary aspergillosis (lung disorder caused by aspergillus fungi)
Convulsion (muscles contract and relax rapidly and repeatedly, resulting in an uncontrolled shaking of the body)

20-29:

Pancreatitis (inflammation of pancreas)
Blood alkaline phosphatase increased
Gamma-glutamyltransferase increased
Hypocalcaemia (levels of calcium in blood serum are abnormally low)
Lymphopenia (an abnormally low level of lymphocytes in the blood)
Neutropenia (an abnormally low number of neutrophils)
Sepsis (a severe blood infection that can lead to organ failure and death)
Thrombocytopenia (decrease of platelets in blood)
Abdominal distension
Diarrhoea

30-39:

n/a

40-49:

n/a

50-59:

Graft versus host disease in intestine (the donated bone marrow or stem cells view the recipient's body as foreign, and the donated cells/bone marrow attack the body and damages intestinal mucosal membrane)
Proctalgia (pain in the rectum)

60+:

Mental status changes (general changes in brain function, such as confusion, amnesia (memory loss), loss of alertness, loss of orientation)
Aspergillosis (an infection caused by a fungus called aspergillus)
Cardiac arrest
Coagulopathy (blood's ability to clot is impaired)
Depressed level of consciousness
Diastolic dysfunction
Drug toxicity
Enterococcal infection
Ileus paralytic (obstruction of the intestine due to paralysis of the intestinal muscles)
Immunosuppression

What are the existing conditions these people have? *

Acute Myeloid Leukaemia (acute cancer in which the bone marrow makes abnormal myeloblasts): 7 people, 36.84%
Acute Lymphocytic Leukemia (All) (cancer of the white blood cells characterized by excess lymphoblasts): 5 people, 26.32%
Acute Myeloid Leukaemia Recurrent (acute cancer in which the bone marrow makes abnormal myeloblast- recurrent): 3 people, 15.79%
Acute Leukaemia (blood cancer): 2 people, 10.53%
Sepsis (a severe blood infection that can lead to organ failure and death): 1 person, 5.26%
Nausea And Vomiting: 1 person, 5.26%
Nausea (feeling of having an urge to vomit): 1 person, 5.26%
Myelodysplastic Syndrome (a group of conditions that occur when the blood-forming cells in the bone marrow are damaged): 1 person, 5.26%
Lymphocytic Leukaemia (a type of cancer in which the bone marrow makes too many lymphocytes): 1 person, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

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