Clonazepam and Bioflavonoids drug interactions - a phase IV clinical study of FDA data
Summary:
Drug interactions are reported among people who take Clonazepam (clonazepam) and Bioflavonoids (grapefruit). Common drug interactions include jaundice cholestatic among females and dyspnoea exertional among males.
The phase IV clinical study analyzes what interactions people have when they take Clonazepam and Bioflavonoids. It is created by eHealthMe based on reports of 16 people who take the same drugs from the FDA, and is updated regularly.
What is Clonazepam?
Clonazepam has active ingredients of clonazepam. It is often used in stress and anxiety. eHealthMe is studying from 146,271 Clonazepam users. Check the latest studies of Clonazepam.
What is Bioflavonoids?
Bioflavonoids has active ingredients of grapefruit. eHealthMe is studying from 302 Bioflavonoids users. Check the latest studies of Bioflavonoids.
eHealthMe: drug outcomes in the real world
eHealthMe runs one of the largest post-marketing drug safety studies in the world. We study millions of patients and 5,000 more each day. Our data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Tools to study our phase IV findings are available to the public, anonymous and free >>>.
16 people who take Clonazepam and Bioflavonoids together, and have interactions are studied.

What are the common drug interactions of Clonazepam and Bioflavonoids, by gender? *:
female:
- Jaundice cholestatic
- Nausea (feeling of having an urge to vomit)
- Psychotic disorder
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Foot fracture
- Weight decreased
- Cough
- Hand fracture
- Respiratory tract congestion (blockage on respiratory system)
male:
- Dyspnoea exertional (breathlessness or shortness of breath)
- Gait disturbance
- Pain in extremity
What are the common drug interactions of Clonazepam and Bioflavonoids, by age (0-1 to 60+)? *:
0-1:
n/a
2-9:
n/a
10-19:
n/a
20-29:
n/a
30-39:
n/a
40-49:
n/a
50-59:
- Blood bilirubin increased
- Cholelithiasis (the presence or formation of gallstones in the gallbladder or bile ducts)
- Hepatic enzyme increased
- Hepatotoxicity (chemical-driven liver damage)
- Hypomania (a mild form of mania, marked by elation and hyperactivity)
- Jaundice cholestatic
- Nausea (feeling of having an urge to vomit)
- Pneumonia
- Psychotic disorder
- Schizophrenia (a mental disorder characterized by a breakdown of thought processes)
60+:
- Pneumonia
- Diabetes mellitus (diabetes, caused by a deficiency of the pancreatic hormone insulin)
- Acne (skin problems that cause pimples)
- Bronchitis (inflammation of the mucous membrane in the bronchial tubes)
- Confusional state
- Dizziness
- Dry mouth
- Dysphagia (a condition in which swallowing is difficult or painful)
- Dyspnoea exertional (breathlessness or shortness of breath)
- Gait disturbance
What are the existing conditions these people have? *
- Hiv Infection: 6 people, 37.50%
- Psychotic Disorder: 6 people, 37.50%
- Depression: 6 people, 37.50%
- Pain In Extremity: 6 people, 37.50%
- Musculoskeletal Stiffness (stiffness of the body's muscles, joints, tendons, ligaments and nerves): 6 people, 37.50%
- Hypomania (a mild form of mania, marked by elation and hyperactivity): 6 people, 37.50%
- Sleep Disorder: 3 people, 18.75%
- Bipolar Disorder (mood disorder): 3 people, 18.75%
- Conjunctivitis (pink eye): 3 people, 18.75%
- Conjunctivitis Allergic (inflammation of the conjunctiva due to allergy): 3 people, 18.75%
* Approximation only. Some reports may have incomplete information.
Do you take Clonazepam and Bioflavonoids?
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Related studies:
Effectiveness of, side effects of, and alternative drugs to the 2 drugs:
- Clonazepam (146,271 reports)
- Bioflavonoids (302 reports)
Browse all drug interactions of Clonazepam and Bioflavonoids:
a b c d e f g h i j k l m n o p q r s t u v w x y zSub-studies by gender and age:
Female: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Male: 0-1 2-9 10-19 20-29 30-39 40-49 50-59 60+
Browse all side effects of Clonazepam:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all side effects of Bioflavonoids:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Clonazepam and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zBrowse all interactions between Bioflavonoids and drugs from A to Z:
a b c d e f g h i j k l m n o p q r s t u v w x y zRelated publications that referenced our studies
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
- McFarlane SI, "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2015 Jan .
- Ashkar AG, Goldberg T, Maraj I, Masters A, McFarlane SI, "Torsades De Pointes Induced by Methadone and Clonazepam Use", International Journal of Medical and Pharmaceutical Case Reports, 2015 Jan .
- McFarlane, S. I. , "Torsades de Pointes induced by Methadone and Clonazepam Use", , 2014 Jan .
How the study uses the data?
The study uses data from the FDA. It is based on clonazepam and grapefruit (the active ingredients of Clonazepam and Bioflavonoids, respectively), and Clonazepam and Bioflavonoids (the brand names). Other drugs that have the same active ingredients (e.g. generic drugs) are not considered. Dosage of drugs is not considered in the study.
How to use the study?
DO NOT STOP MEDICATIONS without first consulting your doctor. If there are any serious or long term adverse effects discovered in the study, discuss the study with your doctor to ensure that proper medication management will be in place if applicable.
Who is eHealthMe?
With medical big data and proven AI/ML algorithms, eHealthMe provides a platform for everyone to run phase IV clinical trials. We study millions of patients and 5,000 more each day. Results of our real-world drug study have been referenced on 800+ peer-reviewed medical publications, including The Lancet, Mayo Clinic Proceedings, and Nature. Our analysis results are available to researchers, health care professionals, patients (testimonials), and software developers (open API).
WARNING, DISCLAIMER, USE FOR PUBLICATION
WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health.
DISCLAIMER: All material available on eHealthMe.com is for informational purposes only, and is not a substitute for medical advice, diagnosis, or treatment provided by a qualified healthcare provider. All information is observation-only. Our phase IV clinical studies alone cannot establish cause-effect relationship. Different individuals may respond to medication in different ways. Every effort has been made to ensure that all information is accurate, up-to-date, and complete, but no guarantee is made to that effect. The use of the eHealthMe site and its content is at your own risk.
If you use this eHealthMe study on publication, please acknowledge it with a citation: study title, URL, accessed date.
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