Clonidine and Caplyta drug interactions - a phase IV clinical study of FDA data

Summary:

Drug interactions are reported among people who take Clonidine (clonidine) and Caplyta (lumateperone tosylate). Common drug interactions include palpitations among females and dystonia among males.

The phase IV clinical study analyzes what interactions people have when they take Clonidine and Caplyta. It is created by eHealthMe based on reports of 19 people who take the same drugs from the FDA, and is updated regularly.

What is Clonidine?

Clonidine has active ingredients of clonidine. It is often used in high blood pressure. eHealthMe is studying from 65,644 Clonidine users. Check the latest studies of Clonidine.

What is Caplyta?

Caplyta has active ingredients of lumateperone tosylate. eHealthMe is studying from 3,109 Caplyta users. Check the latest studies of Caplyta.

On Jul, 09, 2026

19 people who take Clonidine and Caplyta together, and have interactions are studied.

Clonidine and Caplyta drug interactions.

What are the common drug interactions of Clonidine and Caplyta, by gender? *:

female:

Palpitations (feelings or sensations that your heart is pounding or racing)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Fatigue (feeling of tiredness)
Pain
Blood lactic acid increased
Blood pressure diastolic increased
Chest discomfort
Chest pain
Depression
Disturbance in attention

male:

Dystonia (abnormal muscle tone)
Malaise (a feeling of general discomfort or uneasiness)
Disturbance in attention
Fatigue (feeling of tiredness)
Influenza like illness
Muscular weakness (muscle weakness)
Musculoskeletal chest pain (pain in chest muscle or nerve or bones)
Obsessive thoughts (intrusive thoughts that produce uneasiness, apprehension, fear, or worry)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Performance status decreased

What are the common drug interactions of Clonidine and Caplyta, by age (0-1 to 60+)? *:

0-1:

Cognitive disorder (mental health disorders affects learning, memory, perception, and problem solving)
Delusion (a false belief or opinion)
Dissociative disorder
Disturbance in attention
Fatigue (feeling of tiredness)
Influenza like illness
Muscular weakness (muscle weakness)
Obsessive thoughts (intrusive thoughts that produce uneasiness, apprehension, fear, or worry)
Obsessive-compulsive disorder (an anxiety disorder characterized by intrusive thoughts that produce uneasiness, apprehension, fear, or worry;)
Performance status decreased

2-9:

n/a

10-19:

n/a

20-29:

Anaphylactic reaction (serious allergic reaction)
Bruxism (habitual grinding of the teeth, typically during sleep)
Trichotillomania (the compulsive urge to pull out (and in some cases, eat) one's own hair leading to noticeable hair loss, distress)

30-39:

Palpitations (feelings or sensations that your heart is pounding or racing)
Tachycardia (a heart rate that exceeds the range of 100 beats/min)
Blood lactic acid increased
Blood pressure diastolic increased
Burning sensation
Chest discomfort
Chest pain
Depression
Disturbance in attention
Dyspnoea (difficult or laboured respiration)

40-49:

n/a

50-59:

Dry mouth
Fatigue (feeling of tiredness)
Nausea (feeling of having an urge to vomit)
Oedema peripheral (superficial swelling)
Vision blurred
Dystonia (abnormal muscle tone)
Malaise (a feeling of general discomfort or uneasiness)

60+:

Tardive dyskinesia (a disorder that involves involuntary movements)
Dizziness
Fall
Back injury
Head injury
Limb injury
Orthostatic hypotension (a medical condition consisting of a sudden decrease in blood pressure when a person stands up)
Pain

What are the existing conditions these people have? *

Bipolar Disorder (mood disorder): 12 people, 63.16%
Depression: 4 people, 21.05%
Attention Deficit Hyperactivity Disorder (a chronic condition including attention difficulty, hyperactivity, and impulsiveness): 4 people, 21.05%
Stress And Anxiety: 3 people, 15.79%
Schizophrenia (a mental disorder characterized by a breakdown of thought processes): 3 people, 15.79%
Arthritis (form of joint disorder that involves inflammation of one or more joints): 1 person, 5.26%
Bipolar I Disorder (mood disorder that is characterized by at least one manic or mixed episode): 1 person, 5.26%
Blood Pressure Abnormal: 1 person, 5.26%
Constipation: 1 person, 5.26%
Gastroesophageal Reflux Disease (a condition in which stomach contents leak backward from the stomach into the oesophagus): 1 person, 5.26%

* Approximation only. Some reports may have incomplete information.

Do you take Clonidine and Caplyta?

- Personalize this study to your gender, age, symptoms and drugs
- Predict drug outcomes for up to one year with AI
- Get an AI agent to monitor your drugs continuously